Frontiers in Molecular Biosciences | Protein Biochemistry for Basic and Applied Sciences

Original Research

Published on 04 Apr 2023

Inactivation of the lysine binding sites of human plasminogen (hPg) reveals novel structural requirements for the tight hPg conformation, M-protein binding, and rapid activation

in Protein Biochemistry for Basic and Applied Sciences

Yetunde A. Ayinuola
Francis J. Castellino

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1166155

2,381 views
7 citations

Original Research

Published on 28 Mar 2023

3D interaction homology: The hydrophobic residues alanine, isoleucine, leucine, proline and valine play different structural roles in soluble and membrane proteins

in Protein Biochemistry for Basic and Applied Sciences

Mohammed H. AL Mughram
Claudio Catalano
Noah B. Herrington
Martin K. Safo
Glen E. Kellogg

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1116868

12,543 views
39 citations

Original Research

Published on 20 Mar 2023

Identification of a peptide ligand for human ALDH3A1 through peptide phage display: Prediction and characterization of protein interaction sites and inhibition of ALDH3A1 enzymatic activity

in Protein Biochemistry for Basic and Applied Sciences

Georgia-Persephoni Voulgaridou
Vasileios Theologidis
Vasileios Xanthis
Eleni Papagiannaki
Ilias Tsochantaridis
Vasiliki E. Fadouloglou
Aglaia Pappa

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1161111

6,411 views
7 citations

Original Research

Published on 16 Mar 2023

Modulation of plant acetyl-CoA synthetase activity by post-translational lysine acetylation

in Protein Biochemistry for Basic and Applied Sciences

Naazneen Sofeo
Dirk C. Winkelman
Karina Leung
Basil J. Nikolau

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1117921

3,414 views
4 citations

Original Research

Published on 08 Mar 2023

Cellular environment of TTR deposits in an animal model of ATTR—Cardiomyopathy

in Protein Biochemistry for Basic and Applied Sciences

Cristina Teixeira
Helena Sofia Martins
Maria João Saraiva

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1144049

6,053 views
7 citations

Brief Research Report

Published on 08 Mar 2023

Interaction between the α-glucosidases, sucrase-isomaltase and maltase-glucoamylase, in human intestinal brush border membranes and its potential impact on disaccharide digestion

in Protein Biochemistry for Basic and Applied Sciences

Stephanie Tannous
Tammy Stellbrinck
Abdullah Hoter
Hassan Y. Naim

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1160860

6,774 views
17 citations

Editorial

Published on 22 Feb 2023

Editorial: The “proteine 2022” conference

in Protein Biochemistry for Basic and Applied Sciences

Francesco Balestri
Adeline Goulet
Gabriella Tedeschi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1157442

1,902 views

Original Research

Published on 06 Feb 2023

Efficacy of IAPP suppression in mouse and human islets by GLP-1 analogue conjugated antisense oligonucleotide

in Protein Biochemistry for Basic and Applied Sciences

Tatyana Gurlo
Thazha P. Prakash
Zhongying Wang
Maani Archang
Lina Pei
Madeline Rosenberger
Elaine Pirie
Richard G. Lee
Peter C. Butler

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1096286

4,484 views
6 citations

Original Research

Published on 26 Jan 2023

Biochemical characterization and identification of ferulenol and embelin as potent inhibitors of malate:quinone oxidoreductase from Campylobacter jejuni

in Protein Biochemistry for Basic and Applied Sciences

Augustin Tshibaka Kabongo
Rajib Acharjee
Takaya Sakura
Gloria Mavinga Bundutidi
Endah Dwi Hartuti
Cadi Davies
Ozan Gundogdu
Kiyoshi Kita
Tomoo Shiba
Daniel Ken Inaoka

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1095026

6,472 views
4 citations

Original Research

Published on 24 Jan 2023

Dual incorporation of non-canonical amino acids enables production of post-translationally modified selenoproteins

in Protein Biochemistry for Basic and Applied Sciences

Pearl Morosky
Cody Comyns
Lance G. A. Nunes
Christina Z. Chung
Peter R. Hoffmann
Dieter Söll
Oscar Vargas-Rodriguez
Natalie Krahn

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1096261

6,991 views
6 citations

Editorial

Published on 19 Jan 2023

Editorial: Metalloproteins as sensors of gaseous small molecules—From bench to bed and beyond

in Protein Biochemistry for Basic and Applied Sciences

Eduardo H. S. Sousa
Shiliang Tian

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1140392

2,177 views
2 citations

Review

Published on 16 Jan 2023

Involvement of heterologous ubiquitination including linear ubiquitination in Alzheimer’s disease and amyotrophic lateral sclerosis

in Protein Biochemistry for Basic and Applied Sciences

Yusuke Sato
Seigo Terawaki
Daisuke Oikawa
Kouhei Shimizu
Yoshinori Okina
Hidefumi Ito
Fuminori Tokunaga

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1089213

9,557 views
11 citations

Original Research

Published on 11 Jan 2023

Plasma enzymatic activity, proteomics and peptidomics in COVID-19-induced sepsis: A novel approach for the analysis of hemostasis

in Protein Biochemistry for Basic and Applied Sciences

Fernando Dos Santos
Joyce B. Li
Nathalia Juocys
Rafi Mazor
Laura Beretta
Nicole G. Coufal
Michael T. Y. Lam
Mazen F. Odish
Maria Claudia Irigoyen
Anthony J. O’Donoghue

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1051471

3,805 views
8 citations

Brief Research Report

Published on 06 Jan 2023

Structural basis for ubiquitylation by HOIL-1

in Protein Biochemistry for Basic and Applied Sciences

Qilong Wu
Marios G. Koliopoulos
Katrin Rittinger
Benjamin Stieglitz

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1098144

21,817 views
11 citations

Original Research

Published on 05 Jan 2023

Challenges in predicting stabilizing variations: An exploration

in Protein Biochemistry for Basic and Applied Sciences

Silvia Benevenuta
Giovanni Birolo
Tiziana Sanavia
Emidio Capriotti
Piero Fariselli

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1075570

3,342 views
23 citations

Review

Published on 04 Jan 2023

Ending a bad start: Triggers and mechanisms of co-translational protein degradation

in Protein Biochemistry for Basic and Applied Sciences

Tom Joshua Eisenack
Débora Broch Trentini

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1089825

9,898 views
12 citations

Original Research

Published on 04 Jan 2023

Structural and evolutionary insights into astacin metallopeptidases

in Protein Biochemistry for Basic and Applied Sciences

F. Xavier Gomis-Rüth
Walter Stöcker

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1080836

23,703 views
19 citations

Editorial

Published on 14 Dec 2022

Editorial: Molecular determinants of protein assemblies in health and disease

in Protein Biochemistry for Basic and Applied Sciences

Sonja Kroschwald
Anoop Arunagiri
Salvador Ventura
Srivastav Ranganathan
Verena Kohler

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1107686

2,043 views
2 citations

Original Research

Published on 12 Dec 2022

From linoleic acid to hexanal and hexanol by whole cell catalysis with a lipoxygenase, hydroperoxide lyase and reductase cascade in Komagataella phaffii

in Protein Biochemistry for Basic and Applied Sciences

Chiam Hashem
Julius Hochrinner
Moritz B. Bürgler
Claudia Rinnofner
Harald Pichler
Margit Winkler

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.965315

6,563 views
11 citations

Editorial

Published on 02 Dec 2022

Editorial: Machine learning, epistasis, and protein engineering: From sequence-structure-function relationships to regulation of metabolic pathways

in Protein Biochemistry for Basic and Applied Sciences

Frederic Cadet
Emma Saavedra
Per-Olof Syren
Brigitte Gontero

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1098289

4,280 views
2 citations

Original Research

Published on 30 Nov 2022

Co-crystalization reveals the interaction between AtYchF1 and ppGpp

in Protein Biochemistry for Basic and Applied Sciences

Ming-Yan Cheung
Xiaorong Li
Yee-Shan Ku
Zhongzhou Chen
Hon-Ming Lam

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1061350

4,397 views
3 citations

Mini Review

Published on 29 Nov 2022

Identifying individuals using proteomics: are we there yet?

in Protein Biochemistry for Basic and Applied Sciences

Ivo Fierro-Monti
James C. Wright
Jyoti S. Choudhary
Juan Antonio Vizcaíno

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1062031

5,550 views
17 citations

Original Research

Published on 22 Nov 2022

Phosphoproteomic mapping of CCR5 and ACKR2 signaling properties

in Protein Biochemistry for Basic and Applied Sciences

Alessandro Vacchini
Elisa Maffioli
Dario Di Silvestre
Cinzia Cancellieri
Samantha Milanesi
Simona Nonnis
Sabrina Badanai
Pierluigi Mauri
Armando Negri
Massimo Locati

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1060555

3,180 views
2 citations

Review

Published on 22 Nov 2022

Principles and functions of condensate modifying drugs

in Protein Biochemistry for Basic and Applied Sciences

Avinash Patel
Diana Mitrea
Vigneshwaran Namasivayam
Mark A. Murcko
Michael Wagner
Isaac A. Klein

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1007744

14,703 views
41 citations

277 articles

articles

Inactivation of the lysine binding sites of human plasminogen (hPg) reveals novel structural requirements for the tight hPg conformation, M-protein binding, and rapid activation

3D interaction homology: The hydrophobic residues alanine, isoleucine, leucine, proline and valine play different structural roles in soluble and membrane proteins

Identification of a peptide ligand for human ALDH3A1 through peptide phage display: Prediction and characterization of protein interaction sites and inhibition of ALDH3A1 enzymatic activity

Modulation of plant acetyl-CoA synthetase activity by post-translational lysine acetylation

Cellular environment of TTR deposits in an animal model of ATTR—Cardiomyopathy

Interaction between the α-glucosidases, sucrase-isomaltase and maltase-glucoamylase, in human intestinal brush border membranes and its potential impact on disaccharide digestion

Editorial: The “proteine 2022” conference

Efficacy of IAPP suppression in mouse and human islets by GLP-1 analogue conjugated antisense oligonucleotide

Biochemical characterization and identification of ferulenol and embelin as potent inhibitors of malate:quinone oxidoreductase from Campylobacter jejuni

Dual incorporation of non-canonical amino acids enables production of post-translationally modified selenoproteins

Editorial: Metalloproteins as sensors of gaseous small molecules—From bench to bed and beyond

Involvement of heterologous ubiquitination including linear ubiquitination in Alzheimer’s disease and amyotrophic lateral sclerosis

Plasma enzymatic activity, proteomics and peptidomics in COVID-19-induced sepsis: A novel approach for the analysis of hemostasis

Structural basis for ubiquitylation by HOIL-1

Challenges in predicting stabilizing variations: An exploration

Ending a bad start: Triggers and mechanisms of co-translational protein degradation

Structural and evolutionary insights into astacin metallopeptidases

Editorial: Molecular determinants of protein assemblies in health and disease

From linoleic acid to hexanal and hexanol by whole cell catalysis with a lipoxygenase, hydroperoxide lyase and reductase cascade in Komagataella phaffii

Editorial: Machine learning, epistasis, and protein engineering: From sequence-structure-function relationships to regulation of metabolic pathways

Co-crystalization reveals the interaction between AtYchF1 and ppGpp

Identifying individuals using proteomics: are we there yet?

Phosphoproteomic mapping of CCR5 and ACKR2 signaling properties

Principles and functions of condensate modifying drugs