Frontiers in Molecular Biosciences | Protein Biochemistry for Basic and Applied Sciences

Original Research

Published on 12 Dec 2022

From linoleic acid to hexanal and hexanol by whole cell catalysis with a lipoxygenase, hydroperoxide lyase and reductase cascade in Komagataella phaffii

in Protein Biochemistry for Basic and Applied Sciences

Chiam Hashem
Julius Hochrinner
Moritz B. Bürgler
Claudia Rinnofner
Harald Pichler
Margit Winkler

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.965315

7,241 views
13 citations

Editorial

Published on 02 Dec 2022

Editorial: Machine learning, epistasis, and protein engineering: From sequence-structure-function relationships to regulation of metabolic pathways

in Protein Biochemistry for Basic and Applied Sciences

Frederic Cadet
Emma Saavedra
Per-Olof Syren
Brigitte Gontero

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1098289

4,445 views
2 citations

Original Research

Published on 30 Nov 2022

Co-crystalization reveals the interaction between AtYchF1 and ppGpp

in Protein Biochemistry for Basic and Applied Sciences

Ming-Yan Cheung
Xiaorong Li
Yee-Shan Ku
Zhongzhou Chen
Hon-Ming Lam

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1061350

4,575 views
3 citations

Mini Review

Published on 29 Nov 2022

Identifying individuals using proteomics: are we there yet?

in Protein Biochemistry for Basic and Applied Sciences

Ivo Fierro-Monti
James C. Wright
Jyoti S. Choudhary
Juan Antonio Vizcaíno

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1062031

5,751 views
17 citations

Original Research

Published on 22 Nov 2022

Phosphoproteomic mapping of CCR5 and ACKR2 signaling properties

in Protein Biochemistry for Basic and Applied Sciences

Alessandro Vacchini
Elisa Maffioli
Dario Di Silvestre
Cinzia Cancellieri
Samantha Milanesi
Simona Nonnis
Sabrina Badanai
Pierluigi Mauri
Armando Negri
Massimo Locati

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1060555

3,419 views
2 citations

Review

Published on 22 Nov 2022

Principles and functions of condensate modifying drugs

in Protein Biochemistry for Basic and Applied Sciences

Avinash Patel
Diana Mitrea
Vigneshwaran Namasivayam
Mark A. Murcko
Michael Wagner
Isaac A. Klein

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1007744

15,392 views
43 citations

Editorial

Published on 21 Nov 2022

Editorial: NAD+ metabolism as a novel target against infection–Volume II

in Protein Biochemistry for Basic and Applied Sciences

Enrico Balducci
Nady Braidy
Marie Migaud

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1087897

2,302 views
3 citations

Original Research

Published on 14 Nov 2022

Polyanion order controls liquid-to-solid phase transition in peptide/nucleic acid co-assembly

in Protein Biochemistry for Basic and Applied Sciences

Christella Gordon-Kim
Allisandra Rha
George A. Poppitz
Jillian Smith-Carpenter
Regina Luu
Alexis B. Roberson
Russell Conklin
Alexis Blake
David G. Lynn

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.991728

3,998 views
3 citations

Original Research

Published on 07 Nov 2022

Binding pocket stabilization by high-throughput screening of yeast display libraries

in Protein Biochemistry for Basic and Applied Sciences

Jorge A. Lerma Romero
Christian Meyners
Andreas Christmann
Lisa M. Reinbold
Anna Charalampidou
Felix Hausch
Harald Kolmar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1023131

4,870 views
6 citations

Perspective

Published on 03 Nov 2022

Drug discovery by a basic research scientist

in Protein Biochemistry for Basic and Applied Sciences

William A. Eaton

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1062346

2,628 views

Mini Review

Published on 03 Nov 2022

Early processes in heme-based CO-sensing proteins

in Protein Biochemistry for Basic and Applied Sciences

Marten H. Vos
Mayla Salman
Ursula Liebl

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1046412

2,549 views
2 citations

Original Research

Published on 26 Oct 2022

Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII

in Protein Biochemistry for Basic and Applied Sciences

Shaun C. Peters
Kenneth C. Childers
Corbin E. Mitchell
Nathan G. Avery
Steven S. Reese
Cristopher Mitchell
Serena W. Wo
Christopher D. Swanson
Caileen M. Brison
P. Clint Spiegel

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1040106

3,952 views
5 citations

Original Research

Published on 24 Oct 2022

Engineered bacterial host for genetic encoding of physiologically stable protein nitration

in Protein Biochemistry for Basic and Applied Sciences

Nikolaj G. Koch
Tobias Baumann
Jessica H. Nickling
Anna Dziegielewski
Nediljko Budisa

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.992748

5,442 views
15 citations

Mini Review

Published on 19 Oct 2022

ADAMTS6: Emerging roles in cardiovascular, musculoskeletal and cancer biology

in Protein Biochemistry for Basic and Applied Sciences

Timothy J. Mead

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1023511

5,000 views
15 citations

Original Research

Published on 18 Oct 2022

Single-gene knockout-coupled omics analysis identifies C9orf85 and CXorf38 as two uncharacterized human proteins associated with ZIP8 malfunction

in Protein Biochemistry for Basic and Applied Sciences

Heng Wee Tan
Yan-Ming Xu
Zhan-Ling Liang
Na-Li Cai
Yu-Yao Wu
Andy T. Y. Lau

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.991308

4,158 views
4 citations

Mini Review

Published on 14 Oct 2022

Involvement of shedding induced by ADAM17 on the nitric oxide pathway in hypertension

in Protein Biochemistry for Basic and Applied Sciences

Mirelly Cunha da Silva
Vanessa Maria dos Santos
Matheus Vinícius B. da Silva
Tereza Cristina M. M. Prazeres
Maria do Socorro S. Cartágenes
Natália Tabosa M. Calzerra
Thyago Moreira de Queiroz

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1032177

5,421 views
11 citations

Original Research

Published on 11 Oct 2022

Delivery of the selenoprotein thioredoxin reductase 1 to mammalian cells

in Protein Biochemistry for Basic and Applied Sciences

David E. Wright
Tarana Siddika
Ilka U. Heinemann
Patrick O’Donoghue

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1031756

3,214 views
5 citations

Review

Published on 11 Oct 2022

Soluble guanylyl cyclase: Molecular basis for ligand selectivity and action in vitro and in vivo

in Protein Biochemistry for Basic and Applied Sciences

Gang Wu
Iraida Sharina
Emil Martin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1007768

4,393 views
16 citations

Review

Published on 05 Oct 2022

Synthesis, function, and regulation of sterol and nonsterol isoprenoids

in Protein Biochemistry for Basic and Applied Sciences

Rebecca Faulkner
Youngah Jo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1006822

9,930 views
25 citations

Methods

Published on 29 Sep 2022

PUP-IT2 as an alternative strategy for PUP-IT proximity labeling

in Protein Biochemistry for Basic and Applied Sciences

Suyu Yue
Peng Xu
Zhihe Cao
Min Zhuang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1007720

11,273 views
12 citations

Original Research

Published on 26 Sep 2022

Spike S1 domain interactome in non-pulmonary systems: A role beyond the receptor recognition

in Protein Biochemistry for Basic and Applied Sciences

Ilaria Iacobucci
Vittoria Monaco
Luisa Canè
Francesca Bibbò
Valentina Cioffi
Flora Cozzolino
Alfredo Guarino
Massimo Zollo
Maria Monti

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.975570

4,061 views
13 citations

Mini Review

Published on 23 Sep 2022

Possible molecular basis of the biochemical effects of cysteine-derived persulfides

in Protein Biochemistry for Basic and Applied Sciences

Ernesto Cuevasanta
Dayana Benchoam
Jonathan A. Semelak
Matías N. Möller
Ari Zeida
Madia Trujillo
Beatriz Alvarez
Darío A. Estrin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.975988

5,121 views
14 citations

Original Research

Published on 16 Sep 2022

Pathogenic variation types in human genes relate to diseases through Pfam and InterPro mapping

in Protein Biochemistry for Basic and Applied Sciences

Giulia Babbi
Castrense Savojardo
Davide Baldazzi
Pier Luigi Martelli
Rita Casadio

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.966927

3,613 views
1 citation

Mini Review

Published on 14 Sep 2022

Role of USP13 in physiology and diseases

in Protein Biochemistry for Basic and Applied Sciences

Qian Wang
Zhenzhen Sun
Weiwei Xia
Le Sun
Yang Du
Yue Zhang
Zhanjun Jia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.977122

9,102 views
28 citations

283 articles

articles

From linoleic acid to hexanal and hexanol by whole cell catalysis with a lipoxygenase, hydroperoxide lyase and reductase cascade in Komagataella phaffii

Editorial: Machine learning, epistasis, and protein engineering: From sequence-structure-function relationships to regulation of metabolic pathways

Co-crystalization reveals the interaction between AtYchF1 and ppGpp

Identifying individuals using proteomics: are we there yet?

Phosphoproteomic mapping of CCR5 and ACKR2 signaling properties

Principles and functions of condensate modifying drugs

Editorial: NAD+ metabolism as a novel target against infection–Volume II

Polyanion order controls liquid-to-solid phase transition in peptide/nucleic acid co-assembly

Binding pocket stabilization by high-throughput screening of yeast display libraries

Drug discovery by a basic research scientist

Early processes in heme-based CO-sensing proteins

Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII

Engineered bacterial host for genetic encoding of physiologically stable protein nitration

ADAMTS6: Emerging roles in cardiovascular, musculoskeletal and cancer biology

Single-gene knockout-coupled omics analysis identifies C9orf85 and CXorf38 as two uncharacterized human proteins associated with ZIP8 malfunction

Involvement of shedding induced by ADAM17 on the nitric oxide pathway in hypertension

Delivery of the selenoprotein thioredoxin reductase 1 to mammalian cells

Soluble guanylyl cyclase: Molecular basis for ligand selectivity and action in vitro and in vivo

Synthesis, function, and regulation of sterol and nonsterol isoprenoids

PUP-IT2 as an alternative strategy for PUP-IT proximity labeling

Spike S1 domain interactome in non-pulmonary systems: A role beyond the receptor recognition

Possible molecular basis of the biochemical effects of cysteine-derived persulfides

Pathogenic variation types in human genes relate to diseases through Pfam and InterPro mapping

Role of USP13 in physiology and diseases