Frontiers in Molecular Biosciences

Original Research

Published on 02 Mar 2023

Enhancing response of a protein conformational switch by using two disordered ligand binding domains

in Structural Biology

Harsimranjit Sekhon
Jeung-Hoi Ha
Stewart N. Loh

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1114756

4,017 views
9 citations

Original Research

Published on 23 Feb 2023

Binding of RPR260243 at the intracellular side of the hERG1 channel pore domain slows closure of the helix bundle crossing gate

in Structural Biology

Eva-Maria Zangerl-Plessl
Wei Wu
Michael C. Sanguinetti
Anna Stary-Weinzinger

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1137368

2,452 views
2 citations

Original Research

Published on 21 Feb 2023

Learned features of antibody-antigen binding affinity

in Structural Biology

Nathaniel L. Miller
Thomas Clark
Rahul Raman
Ram Sasisekharan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1112738

12,061 views
15 citations

Editorial

Published on 14 Feb 2023

Editorial: Intersection of biophysical and structural approaches in vaccine design

in Structural Biology

Christopher P. Ptak
Ching-Lin Hsieh
James A. Garnett
Rino Rappuoli
Yi-Pin Lin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1142656

2,464 views

Mini Review

Published on 10 Feb 2023

Molecular mechanism of Rubisco activase: Dynamic assembly and Rubisco remodeling

in Structural Biology

Kazi Waheeda
Heidi Kitchel
Quan Wang
Po-Lin Chiu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1125922

16,129 views
29 citations

Original Research

Published on 09 Feb 2023

Conserved gene signatures shared among MAPT mutations reveal defects in calcium signaling

in Structural Biology

Miguel A. Minaya
Sidhartha Mahali
Abhirami K. Iyer
Abdallah M. Eteleeb
Rita Martinez
Guangming Huang
John Budde
Sally Temple
Alissa L. Nana
William W. Seeley

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1051494

7,659 views
24 citations

Methods

Published on 08 Feb 2023

Engineering the kinetic stability of a β-trefoil protein by tuning its topological complexity

in Structural Biology

Delaney M. Anderson
Lakshmi P. Jayanthi
Shachi Gosavi
Elizabeth M. Meiering

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1021733

3,215 views
1 citation

Editorial

Published on 06 Feb 2023

Editorial: From the hydrophobic core to the globular-disorder interface: New challenges and insights into protein design

in Structural Biology

Sankar Basu
Devlina Chakravarty
Qingzhen Hou
Vladimir N. Uversky

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1151676

1,969 views
1 citation

Original Research

Published on 06 Feb 2023

Quantitative comparison of protein-protein interaction interface using physicochemical feature-based descriptors of surface patches

in Structural Biology

Woong-Hee Shin
Keiko Kumazawa
Kenichiro Imai
Takatsugu Hirokawa
Daisuke Kihara

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1110567

6,513 views
3 citations

Editorial

Published on 01 Feb 2023

Editorial: Integration of structural biology data in lead drug discovery and optimization

in Structural Biology

Pietro Roversi
Gianluca Molla
Marco Nardini

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1145834

2,511 views
4 citations

Original Research

Published on 26 Jan 2023

Parameterization of a single H-bond in Orange Carotenoid Protein by atomic mutation reveals principles of evolutionary design of complex chemical photosystems

in Structural Biology

Marcus Moldenhauer
Hsueh-Wei Tseng
Anastasia Kraskov
Neslihan N. Tavraz
Igor A. Yaroshevich
Peter Hildebrandt
Nikolai N. Sluchanko
Georg A. Hochberg
Lars-Oliver Essen
Nediljko Budisa

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1072606

3,514 views
6 citations

Original Research

Published on 25 Jan 2023

Systematic analysis reveals novel insight into the molecular determinants of function, diversity and evolution of sweet taste receptors T1R2/T1R3 in primates

in Structural Biology

Congrui Wang
Yi Liu
Meng Cui
Bo Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1037966

4,993 views
5 citations

Editorial

Published on 23 Jan 2023

Editorial: Symmetry in protein architecture: Evolution, design, structure-function relationship, and applications

in Structural Biology

Michael Blaber
Suman Kundu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1140877

2,272 views
1 citation

Perspective

Published on 23 Jan 2023

Perspective: Structure determination of protein-ligand complexes at room temperature using X-ray diffraction approaches

in Structural Biology

Michael A. Hough
Filippo Prischi
Jonathan A. R. Worrall

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1113762

6,762 views
8 citations

Editorial

Published on 17 Jan 2023

Editorial: Structure-function metrology of proteins

in Structural Biology

Alex R. Jones
Isabel Moraes
Milena Quaglia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1125791

1,850 views
1 citation

Original Research

Published on 13 Jan 2023

A new and efficient procedure to load bioactive molecules within the human heavy-chain ferritin nanocage

in Structural Biology

Rosanna Lucignano
Ilaria Stanzione
Giarita Ferraro
Rocco Di Girolamo
Carolina Cané
Angela Di Somma
Angela Duilio
Antonello Merlino
Delia Picone

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1008985

5,387 views
15 citations