Frontiers in Molecular Neuroscience | Brain Disease Mechanisms

Review

Published on 14 Jan 2025

Novel strategies targeting mitochondria-lysosome contact sites for the treatment of neurological diseases

in Brain Disease Mechanisms

Yinyin Xie
Wenlin Sun
Aoya Han
Xinru Zhou
Shijie Zhang
Changchang Shen
Yi Xie
Cui Wang
Nanchang Xie

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1527013

2,768 views
1 citation

Editorial

Published on 13 Jan 2025

Editorial: Oxytosis/ferroptosis: unraveling the mechanisms and its multifaceted role in neurodegenerative diseases

in Brain Disease Mechanisms

Nawab John Dar
David Soriano Castell
Shahnawaz Ali Bhat
Pamela Maher

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1547301

1,290 views

Original Research

Published on 10 Jan 2025

Serum metabolomic signatures of patients with rare neurogenetic diseases: an insight into potential biomarkers and treatment targets

in Brain Disease Mechanisms

Nalaka Wijekoon
Lakmal Gonawala
Pyara Ratnayake
Darshana Sirisena
Harsha Gunasekara
Athula Dissanayake
Dhammika Amaratunga
Harry W. M. Steinbusch
Yetrib Hathout
Eric P. Hoffman

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1482999

1,711 views

Original Research

Published on 10 Jan 2025

Neurotherapeutic impact of vanillic acid and ibudilast on the cuprizone model of multiple sclerosis

in Brain Disease Mechanisms

Rasha M. Alderbi
Mohammad Z. Alam
Badrah S. Alghamdi
Hadeil M. Alsufiani
Gamal S. Abd El-Aziz
Ulfat M. Omar
Maryam A. Al-Ghamdi

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1503396

1,588 views
1 citation

Review

Published on 07 Jan 2025

Genetic and molecular mechanisms of hydrocephalus

in Brain Disease Mechanisms

Xuehai Deng
Yiqian Chen
Qiyue Duan
Jianlin Ding
Zhong Wang
Junchi Wang
Xinlong Chen
Liangxue Zhou
Long Zhao

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1512455

2,242 views

Review

Published on 24 Dec 2024

The role of Aha1 in cancer and neurodegeneration

in Brain Disease Mechanisms

Brian S.J. Blagg
Kevin C. Catalfano

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1509280

1,387 views

Original Research

Published on 20 Dec 2024

Analysis of the pathogenicity and pathological characteristics of NOTCH3 gene-sparing cysteine mutations in vitro and in vivo models

in Brain Disease Mechanisms

Zhenping Gong
Wan Wang
Ying Zhao
Yadan Wang
Ruihua Sun
Haohan Zhang
Fengyu Wang
Yaru Lu
Jiewen Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1391040

1,654 views

Original Research

Published on 18 Dec 2024

Circulating miR-134 in mesial temporal lobe epilepsy: implications in hippocampal sclerosis development and drug resistance

in Brain Disease Mechanisms

Bárbara Guerra Leal
Cláudia Carvalho
Cristina Santos
Raquel Samões
Ricardo Martins-Ferreira
Catarina Teixeira
Diana Rodrigues
Joel Freitas
Carolina Lemos
Rui Chorão

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1512860

1,173 views

Original Research

Published on 12 Dec 2024

Excitatory neuron-prone prion propagation and excitatory neuronal loss in prion-infected mice

in Brain Disease Mechanisms

Temuulen Erdenebat
Yusuke Komatsu
Nozomi Uwamori
Misaki Tanaka
Takashi Hoshika
Takeshi Yamasaki
Ayano Shimakura
Akio Suzuki
Toyotaka Sato
Motohiro Horiuchi

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1498142

1,679 views
1 citation

Review

Published on 11 Dec 2024

Chaperones vs. oxidative stress in the pathobiology of ischemic stroke

in Brain Disease Mechanisms

Vladislav Soldatov
Artem Venediktov
Andrei Belykh
Gennadii Piavchenko
Mukhammad David Naimzada
Nastasya Ogneva
Natalia Kartashkina
Olga Bushueva

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1513084

2,637 views
2 citations

Perspective

Published on 10 Dec 2024

Development of KCC2 therapeutics to treat neurological disorders

in Brain Disease Mechanisms

Shilpa D. Kadam
Shane V. Hegarty

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1503070

3,576 views

Original Research

Published on 05 Dec 2024

Transcorneal electrical stimulation restores DNA methylation changes in retinal degeneration

in Brain Disease Mechanisms

Ben Yi Tew
Gerald C. Gooden
Pei-An Lo
Dimitrios Pollalis
Brandon Ebright
Alex J. Kalfa
Alejandra Gonzalez-Calle
Biju Thomas
David N. Buckley
Thomas Simon

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1484964

1,467 views
1 citation

Correction

Published on 04 Dec 2024

Corrigendum: Mechanisms of mitophagy and oxidative stress in cerebral ischemia–reperfusion, vascular dementia, and Alzheimer's disease

in Brain Disease Mechanisms

Yujie Lyu
Zhipeng Meng
Yunyun Hu
Bing Jiang
Jiao Yang
Yiqin Chen
Jun Zhou
Mingcheng Li
Huping Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1507345

839 views
1 citation

Editorial

Published on 26 Nov 2024

Editorial: Antiviral drugs: neurotoxicity and neurodevelopmental effects

in Brain Disease Mechanisms

Isabella Zanella
Daniela Zizioli
Eugenia Quiros-Roldan
Aditya N. Bade

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1526357

856 views

Original Research

Published on 22 Nov 2024

Increased nuclear import characterizes aberrant nucleocytoplasmic transport in neurons from patients with spinocerebellar ataxia type 7

in Brain Disease Mechanisms

Joshua G. Macopson-Jones
Maile Adams
Julien Philippe
Albert R. La Spada

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1478110

1,598 views

Review

Published on 22 Nov 2024

Regulation of adult neurogenesis: the crucial role of astrocytic mitochondria

in Brain Disease Mechanisms

Danping Liu
Pei Guo
Yi Wang
Weihong Li

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1516119

2,441 views
1 citation