Frontiers in Molecular Neuroscience | Brain Disease Mechanisms

Review

Published on 29 Aug 2024

A transporter’s doom or destiny: SLC6A1 in health and disease, novel molecular targets and emerging therapeutic prospects

in Brain Disease Mechanisms

Nikita Shah
Ameya S. Kasture
Florian P. Fischer
Harald H. Sitte
Thomas Hummel
Sonja Sucic

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1466694

6,136 views
10 citations

Original Research

Published on 26 Aug 2024

Ovariectomy exacerbates the disturbance of excitation- inhibition balance in the brain of APP/PS-1/tau mice

in Brain Disease Mechanisms

Fuwang Liu
Yanman Liu
Xuri Shen
Jiarui Du
Hanting Zhang
Xueqin Hou

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1391082

3,082 views
3 citations

Hypothesis and Theory

Published on 26 Aug 2024

Potential roles of voltage-gated ion channel disruption in Tuberous Sclerosis Complex

in Brain Disease Mechanisms

Hailey X. Egido-Betancourt
Roy E. Strowd III
Kimberly F. Raab-Graham

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1404884

2,271 views

Original Research

Published on 23 Aug 2024

Age-related changes in the architecture and biochemical markers levels in motor-related cortical areas of SHR rats—an ADHD animal model

in Brain Disease Mechanisms

E. Bogdańska-Chomczyk
P. Wojtacha
M. L Tsai
A. C. W Huang
A. Kozłowska

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1414457

3,633 views
3 citations

Original Research

Published on 21 Aug 2024

Proteomic characterization of head and neck paraganglioma and its molecular classification

in Brain Disease Mechanisms

Xi Wang
Jiameng Sun
Guodong Feng
Xu Tian
Yang Zhao
Zhiqiang Gao
Wei Sun

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1391568

2,165 views
1 citation

Original Research

Published on 20 Aug 2024

A single intravenous reelin injection restores corticosterone-induced neurochemical and behavioral alterations in dams during the post-partum period

in Brain Disease Mechanisms

Carla L. Sánchez-Lafuente
Jenessa N. Johnston
Brady S. Reive
Kaylene K. A. Scheil
Ciara S. Halvorson
Mariana Jimenez
Darian Colpitts
Lisa E. Kalynchuk
Hector J. Caruncho

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1442332

2,930 views
3 citations

Brief Research Report

Published on 16 Aug 2024

Concentrations of glutamate and N-acetylaspartate detected by magnetic resonance spectroscopy in the rat hippocampus correlate with hippocampal-dependent spatial memory performance

in Brain Disease Mechanisms

João M. N. Duarte

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1458070

2,206 views
6 citations

Review

Published on 09 Aug 2024

Novel strategies in Parkinson’s disease treatment: a review

in Brain Disease Mechanisms

Charles L. Mitchell
Dmitry Kurouski

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1431079

11,683 views
13 citations

Original Research

Published on 07 Aug 2024

Interleukin-10 contrasts inflammatory synaptopathy and central neurodegenerative damage in multiple sclerosis

in Brain Disease Mechanisms

Luana Gilio
Diego Fresegna
Mario Stampanoni Bassi
Alessandra Musella
Francesca De Vito
Sara Balletta
Krizia Sanna
Silvia Caioli
Luigi Pavone
Giovanni Galifi

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1430080

3,429 views
3 citations

Review

Published on 07 Aug 2024

Mechanisms of mitophagy and oxidative stress in cerebral ischemia–reperfusion, vascular dementia, and Alzheimer’s disease

in Brain Disease Mechanisms

Yujie Lyu
Zhipeng Meng
Yunyun Hu
Bing Jiang
Jiao Yang
Yiqin Chen
Jun Zhou
Mingcheng Li
Huping Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1394932

9,274 views
30 citations

Review

Published on 31 Jul 2024

Mechanism and treatment of intracerebral hemorrhage focus on mitochondrial permeability transition pore

in Brain Disease Mechanisms

Jing Cong
Jing-Yi Li
Wei Zou

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1423132

7,059 views
9 citations

Original Research

Published on 30 Jul 2024

Multiple aspects of amyloid dynamics in vivo integrate to establish prion variant dominance in yeast

in Brain Disease Mechanisms

Jennifer Norton
Nicole Seah
Fabian Santiago
Suzanne S. Sindi
Tricia R. Serio

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1439442

2,229 views
1 citation

Review

Published on 29 Jul 2024

Molecular signatures in Mendelian neurodevelopment: a focus on ubiquitination driven DNA methylation aberrations

in Brain Disease Mechanisms

Liselot van der Laan
Nicky ten Voorde
Marcel M. A. M. Mannens
Peter Henneman

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1446686

3,340 views
2 citations

Review

Published on 24 Jul 2024

Down syndrome and DYRK1A overexpression: relationships and future therapeutic directions

in Brain Disease Mechanisms

Aidan J. Murphy
Steve D. Wilton
May T. Aung-Htut
Craig S. McIntosh

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1391564

9,471 views
13 citations

Review

Published on 18 Jul 2024

Stress and the gut-brain axis: an inflammatory perspective

in Brain Disease Mechanisms

Julia Morys
Andrzej Małecki
Marta Nowacka-Chmielewska

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1415567

15,533 views
37 citations

Review

Published on 09 Jul 2024

Copper toxicity and deficiency: the vicious cycle at the core of protein aggregation in ALS

in Brain Disease Mechanisms

Jin-Hong Min
Heela Sarlus
Robert A. Harris

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1408159

9,884 views
20 citations

Mini Review

Published on 25 Jun 2024

Downregulation of hsa-miR-132 and hsa-miR-129: non-coding RNA molecular signatures of Alzheimer’s disease

in Brain Disease Mechanisms

Siranjeevi Nagaraj
Carolina Quintanilla-Sánchez
Kunie Ando
Lidia Lopez-Gutierrez
Emilie Doeraene
Andreea-Claudia Kosa
Emmanuel Aydin
Jean-Pierre Brion
Karelle Leroy

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1423340

3,053 views
7 citations

Review

Published on 19 Jun 2024

The role of Foxo3a in neuron-mediated cognitive impairment

in Brain Disease Mechanisms

Qin-Qin Liu
Gui-Hua Wu
Xiao-Chun Wang
Xiao-Wen Xiong
Rui-Wang
Bao-Le Yao

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1424561

6,475 views
14 citations

Review

Published on 17 Jun 2024

Tackling neurodegeneration in vitro with omics: a path towards new targets and drugs

in Brain Disease Mechanisms

Caterina Carraro
Jessica V. Montgomery
Julien Klimmt
Dominik Paquet
Joachim L. Schultze
Marc D. Beyer

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1414886

7,242 views
9 citations

Review

Published on 12 Jun 2024

Mechanisms of inflammation after ischemic stroke in brain-peripheral crosstalk

in Brain Disease Mechanisms

Ling Xie
Ming He
Caidi Ying
Haifeng Chu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1400808

10,314 views
32 citations

Mini Review

Published on 10 Jun 2024

Potential of ferroptosis and ferritinophagy in migraine pathogenesis

in Brain Disease Mechanisms

Michal Fila
Lukasz Przyslo
Marcin Derwich
Jolanta Luniewska-Bury
Elzbieta Pawlowska
Janusz Blasiak

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1427815

3,505 views
3 citations

Mini Review

Published on 30 May 2024

Microglia and infiltrating macrophages in ictogenesis and epileptogenesis

in Brain Disease Mechanisms

Sonja Bröer
Alberto Pauletti

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1404022

3,912 views
8 citations

Opinion

Published on 28 May 2024

CDGSH iron-sulfur domain 2 as a therapeutic target for stroke: an opinion article

in Brain Disease Mechanisms

Chao-Kang Feng
Wei-Jung Chen
Woon-Man Kung
Yu-Yo Sun
Muh-Shi Lin

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1386118

1,643 views

Review

Published on 23 May 2024

Post-stroke cognitive impairment: exploring molecular mechanisms and omics biomarkers for early identification and intervention

in Brain Disease Mechanisms

Qiuyi Lu
Anqi Yu
Juncai Pu
Dawei Chen
Yujie Zhong
Dingqun Bai
Lining Yang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1375973

7,794 views
11 citations

1,115 articles

articles

A transporter’s doom or destiny: SLC6A1 in health and disease, novel molecular targets and emerging therapeutic prospects

Ovariectomy exacerbates the disturbance of excitation- inhibition balance in the brain of APP/PS-1/tau mice

Potential roles of voltage-gated ion channel disruption in Tuberous Sclerosis Complex

Age-related changes in the architecture and biochemical markers levels in motor-related cortical areas of SHR rats—an ADHD animal model

Proteomic characterization of head and neck paraganglioma and its molecular classification

A single intravenous reelin injection restores corticosterone-induced neurochemical and behavioral alterations in dams during the post-partum period

Concentrations of glutamate and N-acetylaspartate detected by magnetic resonance spectroscopy in the rat hippocampus correlate with hippocampal-dependent spatial memory performance

Novel strategies in Parkinson’s disease treatment: a review

Interleukin-10 contrasts inflammatory synaptopathy and central neurodegenerative damage in multiple sclerosis

Mechanisms of mitophagy and oxidative stress in cerebral ischemia–reperfusion, vascular dementia, and Alzheimer’s disease

Mechanism and treatment of intracerebral hemorrhage focus on mitochondrial permeability transition pore

Multiple aspects of amyloid dynamics in vivo integrate to establish prion variant dominance in yeast

Molecular signatures in Mendelian neurodevelopment: a focus on ubiquitination driven DNA methylation aberrations

Down syndrome and DYRK1A overexpression: relationships and future therapeutic directions

Stress and the gut-brain axis: an inflammatory perspective

Copper toxicity and deficiency: the vicious cycle at the core of protein aggregation in ALS

Downregulation of hsa-miR-132 and hsa-miR-129: non-coding RNA molecular signatures of Alzheimer’s disease

The role of Foxo3a in neuron-mediated cognitive impairment

Tackling neurodegeneration in vitro with omics: a path towards new targets and drugs

Mechanisms of inflammation after ischemic stroke in brain-peripheral crosstalk

Potential of ferroptosis and ferritinophagy in migraine pathogenesis

Microglia and infiltrating macrophages in ictogenesis and epileptogenesis

CDGSH iron-sulfur domain 2 as a therapeutic target for stroke: an opinion article

Post-stroke cognitive impairment: exploring molecular mechanisms and omics biomarkers for early identification and intervention