Frontiers in Molecular Neuroscience | Neuroplasticity and Development

Original Research

Accepted on 12 Dec 2025

Omaveloxolone promotes functional recovery of spinal cord injury by reducing inflammatory response and regulating macrophage polarization

in Neuroplasticity and Development

Pengtian Zhao
Wenlu Yuan
Jiayi Zhang
Erke Gao
Dejing Zhang
Zhuolin Wu
Yue Zhang
Junbo Chen
Dunxu Hu
Baoyou Fan

Frontiers in Molecular Neuroscience

Opinion

Published on 03 Dec 2025

Reelin signaling as a translational rheostat: linking synaptic homeostasis to neurodevelopment and neurodegeneration

in Neuroplasticity and Development

Murat S. Durakoglugil

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1731914

525 views

Review

Published on 10 Nov 2025

The transcriptional and cellular landscape of cognitive resilience to Alzheimer’s disease

in Neuroplasticity and Development

Nina Khera
Ravikiran M. Raju
Stuart A. Lipton

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1665802

1,222 views

Original Research

Published on 14 Oct 2025

PGC-1α promotes the survival of newborn neurons within AD hippocampus through activation of the FNDC5/BDNF/TrkB signaling pathway

in Neuroplasticity and Development

Yi-Jie Wang
Yu-Xin Wang
Cheng-Zhi Zou
Wei-Jun Zhang
Wen Pan
Jia-Qing Wang
Hua Wang
Xin Qian
Guo-Jia-Hao Han
Feng-Guo Liu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1688694

1,550 views

Correction

Published on 26 Sep 2025

Correction: Neuroprotective effects of the pannexin-1 channel inhibitor: probenecid on spinal cord injury in rats

in Neuroplasticity and Development

Qi Qi
Xiao-Xuan Wang
Jing-Lu Li
Yu-Qing Chen
Jian-Rong Chang
Jin Xi
He-Zuo Lü
Yu-Xin Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1698001

1,681 views

Original Research

Published on 04 Sep 2025

Identifying biomarkers of hepatic fatty acid metabolism disorder in sevoflurane-induced brain developmental injury by bioinformatics analysis

in Neuroplasticity and Development

Haozheng Yuan
Yuying Lv
Pei Fan
Pengyu Jia
Kui Wang
Kailing Hu
Haodong Sun
Xinlin Chen
Pengbo Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1369365

2,319 views

Editorial

Published on 01 Jul 2025

Editorial: Come as you R(NA): post-transcriptional regulation will do the rest

in Neuroplasticity and Development

Oriane Mauger
Michael A. Kiebler
Clémence Bernard

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1644067

2,359 views

Review

Published on 02 May 2025

Exploring perspectives of Dscam for cognitive deficits: a review of multifunction for regulating neural wiring in homeostasis

in Neuroplasticity and Development

Yinyi Xiong
Li Li
Xiaorong Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1575348

3,401 views
2 citations

Editorial

Published on 11 Mar 2025

Editorial: Mechanisms of auditory development, maintenance, damage, and protection

in Neuroplasticity and Development

Ruosha Lai
Lihua Li
Su-Hua Sha

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1580793

1,297 views

Editorial

Published on 06 Mar 2025

Editorial: Editors' showcase: neuroplasticity and development

in Neuroplasticity and Development

Giovanni Cirillo
Michele Papa

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1558715

1,908 views

Original Research

Published on 26 Feb 2025

Profiling hippocampal neuronal populations reveals unique gene expression mosaics reflective of connectivity-based degeneration in the Ts65Dn mouse model of Down syndrome and Alzheimer’s disease

in Neuroplasticity and Development

Melissa J. Alldred
Kyrillos W. Ibrahim
Harshitha Pidikiti
Sang Han Lee
Adriana Heguy
Gabriela Chiosis
Elliott J. Mufson
Grace E. Stutzmann
Stephen D. Ginsberg

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1546375

3,714 views
2 citations

Original Research

Published on 20 Feb 2025

Astrocyte-secreted factors modulate synaptic protein synthesis as revealed by puromycin labeling of isolated synaptosomes

in Neuroplasticity and Development

Aida de la Cruz-Gambra
Jimena Baleriola

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1427036

2,931 views
3 citations

Editorial

Published on 07 Feb 2025

Editorial: Spatio-temporal molecular mechanisms regulating synapse function and neural circuit dynamics

in Neuroplasticity and Development

Tomohisa Hosokawa
Yoshiyuki Kubota
Tetsuya Takano

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1564028

1,930 views

Editorial

Published on 06 Feb 2025

Editorial: Latest advances in neuroscience at the 9th Croatian Neuroscience Congress

in Neuroplasticity and Development

Kristina Mlinac-Jerkovic
Marija Heffer
Svjetlana Kalanj-Bognar
Senka Blažetić

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1563899

1,537 views

Original Research

Published on 22 Jan 2025

A localized tracing technique to explore intra-amygdala functional and structural correlates of individual variability in behavioral response

in Neuroplasticity and Development

Allie Lipshutz
Victoria Saltz
Kristin R. Anderson
Alessia Manganaro
Dani Dumitriu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1347539

1,776 views

Original Research

Published on 06 Jan 2025

Modeling of auditory neuropathy spectrum disorders associated with the TEME43 variant reveals impaired gap junction function of iPSC-derived glia-like support cells

in Neuroplasticity and Development

Xiaoming Kang
Lu Ma
Jie Wen
Wei Gong
Xianlin Liu
Yihan Hu
Zhili Feng
Qiancheng Jing
Yuexiang Cai
Sijun Li

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1457874

2,382 views

Review

Published on 23 Dec 2024

Post-transcriptional regulation of the transcriptional apparatus in neuronal development

in Neuroplasticity and Development

Mohammad Nazim

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1483901

3,734 views
7 citations

Original Research

Published on 16 Dec 2024

VNS paired with training enhances recognition memory: mechanistic insights from proteomic analysis of the hippocampal synapse

in Neuroplasticity and Development

Seung H. Jung
Laura K. Olsen
Krysten A. Jones
Raquel J. Moore
Sean W. Harshman
Candice N. Hatcher-Solis

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1452327

2,671 views
2 citations

Original Research

Published on 02 Dec 2024

Cell-autonomous action of Slit2 in radial migration of cortical projection neurons

in Neuroplasticity and Development

Tian Jiang
Guozhen Niu
Chunping Wu
Xiaomeng Tu
Jian Xiao
Xue Li
Jie-Guang Chen
Huateng Cao

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1505434

2,041 views
1 citation

Hypothesis and Theory

Published on 27 Nov 2024

Toll-like receptors as a missing link in Notch signaling cascade during neurodevelopment

in Neuroplasticity and Development

Mario Stojanovic
Svjetlana Kalanj-Bognar

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1465023

2,410 views

Original Research

Published on 26 Nov 2024

Optogenetic elevation of postsynaptic cGMP in the hippocampal dentate gyrus enhances LTP and modifies mouse behaviors

in Neuroplasticity and Development

Jelena Borovac
Jayant Rai
Megan Valencia
Hang Li
John Georgiou
Graham L. Collingridge
Keizo Takao
Kenichi Okamoto

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1479360

4,973 views
1 citation

Editorial

Published on 22 Nov 2024

Editorial: Regulators of synapse formation: understanding the molecular mechanisms and its dysregulation in neurodevelopmental disorders

in Neuroplasticity and Development

Takeshi Uemura

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1521380

1,566 views

Perspective

Published on 22 Nov 2024

The good, the bad, and the unknown nature of decreased GD3 synthase expression

in Neuroplasticity and Development

Borna Puljko
Josip Grbavac
Vinka Potočki
Katarina Ilic
Barbara Viljetić
Svjetlana Kalanj-Bognar
Marija Heffer
Željko Debeljak
Senka Blažetić
Kristina Mlinac-Jerkovic

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1465013

2,172 views

Original Research

Published on 06 Nov 2024

Exploring the role of Cdk5 on striatal synaptic plasticity in a 3-NP-induced model of early stages of Huntington’s disease

in Neuroplasticity and Development

Elizabeth Hernández-Echeagaray
Jorge A. Miranda-Barrientos
Elizabeth Nieto-Mendoza
Francisco Miguel Torres-Cruz

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1362365

2,145 views
1 citation

805 articles

articles

Omaveloxolone promotes functional recovery of spinal cord injury by reducing inflammatory response and regulating macrophage polarization

Reelin signaling as a translational rheostat: linking synaptic homeostasis to neurodevelopment and neurodegeneration

The transcriptional and cellular landscape of cognitive resilience to Alzheimer’s disease

PGC-1α promotes the survival of newborn neurons within AD hippocampus through activation of the FNDC5/BDNF/TrkB signaling pathway

Correction: Neuroprotective effects of the pannexin-1 channel inhibitor: probenecid on spinal cord injury in rats

Identifying biomarkers of hepatic fatty acid metabolism disorder in sevoflurane-induced brain developmental injury by bioinformatics analysis

Editorial: Come as you R(NA): post-transcriptional regulation will do the rest

Exploring perspectives of Dscam for cognitive deficits: a review of multifunction for regulating neural wiring in homeostasis

Editorial: Mechanisms of auditory development, maintenance, damage, and protection

Editorial: Editors' showcase: neuroplasticity and development

Profiling hippocampal neuronal populations reveals unique gene expression mosaics reflective of connectivity-based degeneration in the Ts65Dn mouse model of Down syndrome and Alzheimer’s disease

Astrocyte-secreted factors modulate synaptic protein synthesis as revealed by puromycin labeling of isolated synaptosomes

Editorial: Spatio-temporal molecular mechanisms regulating synapse function and neural circuit dynamics

Editorial: Latest advances in neuroscience at the 9th Croatian Neuroscience Congress

A localized tracing technique to explore intra-amygdala functional and structural correlates of individual variability in behavioral response

Modeling of auditory neuropathy spectrum disorders associated with the TEME43 variant reveals impaired gap junction function of iPSC-derived glia-like support cells

Post-transcriptional regulation of the transcriptional apparatus in neuronal development

VNS paired with training enhances recognition memory: mechanistic insights from proteomic analysis of the hippocampal synapse

Cell-autonomous action of Slit2 in radial migration of cortical projection neurons

Toll-like receptors as a missing link in Notch signaling cascade during neurodevelopment

Optogenetic elevation of postsynaptic cGMP in the hippocampal dentate gyrus enhances LTP and modifies mouse behaviors

Editorial: Regulators of synapse formation: understanding the molecular mechanisms and its dysregulation in neurodevelopmental disorders

The good, the bad, and the unknown nature of decreased GD3 synthase expression

Exploring the role of Cdk5 on striatal synaptic plasticity in a 3-NP-induced model of early stages of Huntington’s disease