SYSTEMATIC REVIEW article

Front. Neurol.

Sec. Neurorehabilitation

Volume 16 - 2025 | doi: 10.3389/fneur.2025.1544008

This article is part of the Research TopicCognitive Strategies in motor learning and RehabilitationView all 9 articles

A Systematic Review of Alterations in Brain Activation and Intensity Following Stroke: Implications for Integration and Functional Outcomes

Provisionally accepted
  • National University of Malaysia, Bangi, Malaysia

The final, formatted version of the article will be published soon.

• Increased brain activity and activation intensity are linked to improved clinical outcomes in stroke patients• Neuroplasticity plays a key role in stroke recovery by enabling brain reorganization.• Targeted rehabilitation strategies can effectively promote neuroplasticity, aiding motor and cognitive recovery.• Genetic factors, such as variations in BNDF gene, influence recovery, with certain variants linked to poorer outcomes.• Biomarkers, like perineal angiogenesis, can provide insights into stroke recovery trajectories and prognosis.• The findings emphasize the importance of personalized rehabilitation approaches to optimize recovery.

Keywords: ischaemic stroke, Haemorrhage stroke, -based functional magnetic resonance imaging, Rehabilitation, Brain activity, Neurorehabiliation, Compenation

Received: 12 Dec 2024; Accepted: 06 May 2025.

Copyright: © 2025 Azri, Yahya, Nabilah Ismail, Ashari and Abdul Manan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Amirul Azri, National University of Malaysia, Bangi, Malaysia

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