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SYSTEMATIC REVIEW article

Front. Neurol.

Sec. Experimental Therapeutics

Volume 16 - 2025 | doi: 10.3389/fneur.2025.1545611

The effects of music intervention on pediatric burn patients during treatment: a systematic review and meta-analysis

Provisionally accepted
Bin  ChenBin Chen1*Riti  QiuRiti Qiu2Hua  HuangHua Huang3
  • 1Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China
  • 2Music College, Sichuan Normal University, Chengdu, Sichuan Province, China
  • 3Longquanyi District of Chengdu Maternity and Child Health Care Hospital, Chengdu, Sichuan Province, China

The final, formatted version of the article will be published soon.

Background: Burns rank among the foremost causes of accidental death and injury in children and pediatric patients, and their treatment poses significant challenges. Music intervention has demonstrated considerable potential in alleviating pain and anxiety in pediatric burn patients during treatment. The present meta-analysis was designed to assess the impact of music intervention on the treatment of pediatric burn patients.We conducted a comprehensive search across multiple databases, including PubMed, Web of Science, Embase, and Cochrane Library, to identify studies that met inclusion criteria. Only RCTs published in English that evaluated the efficacy of music intervention in pediatric burn patients were considered eligible for inclusion.The quality assessment of the included studies was performed using the Cochrane risk-of-bias tool. This study was performed based on the Guidelines of Systematic Reporting of Examination presented in the PRISMA checklist. The search protocol has been registered at the PROSPERO International Prospective Register of Systematic Reviews.Results: Four RCTs met the inclusion criteria, involving 158 pediatric burn patients aged from 1 day to 20 years who received either live music therapy or recorded music.Overall, a statistically significant positive effect was observed on both pain (SMD = -0.43, 95% CI [-0.80, -0.07]) and anxiety (SMD = -0.66, 95% CI [-1.05, -0.28]).However, the music intervention group did not show a statistically significant reduction in heart rate (SMD: 0.20, 95% CI [-0.49, 0.89]) or respiratory rate (SMD: -0.21, 95% CI [-0.90, 0.47]).Findings from this study indicates that Music intervention has a positive effect in alleviating pain and reducing anxiety in children and adolescents with burn injuries.

Keywords: Burn pediatric, Music interventions, Pain, Anxiety, Meta-analysis

Received: 02 Jan 2025; Accepted: 24 Jul 2025.

Copyright: © 2025 Chen, Qiu and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Bin Chen, Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.