ORIGINAL RESEARCH article
Front. Neurol.
Sec. Neurotechnology
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1551742
Comparison of perioperative blood loss of three different posterior nonfusion decompression operations for single-segment lumbar disc herniation
Provisionally accepted
- Department of Orthopaedics, The Third Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
The perioperative blood loss of percutaneous endoscopic interlaminar discectomy (PEID), unilateral biportal endoscopic (UBE) and open fenestration discectomy (OPD) was compared to provide reference for the selection of clinical surgical methods. Methods: The clinical data of 260 patients with lumbar disc herniation who underwent PEID, UBE or OPD surgery from March 2020 to February 2024 were retrospectively analyzed, including 100 patients who received PEID surgery, 100 patients who received UBE surgery, and 60 patients who received OPD surgery. Total blood loss and hidden blood loss were calculated according to the linear equation of circulating blood volume, and the hidden blood loss was statistically compared among the three groups. Results: In terms of perioperative total blood loss and visible blood loss, the OPD group had the highest total blood loss (408.46 ± 116.89 ml) and visible blood loss (127.17 ± 24.22 ml), followed by the UBE group (304.46 ± 87.55 ml and 51.00 ± 11.15 ml respectively). The PEID group was the least (152.87± 54.48ml and 18.75 ± 5.09ml). Both the overall differences among the three groups and the pairwise differences were statistically significant (P<0.05). As for hidden blood loss, the results indicated significant differences between the PEID and UBE groups (P < 0.05), as well as between the PEID and OPD groups (P < 0.05). However, no significant difference was observed between the OPD group and the UBE group (P = 0.22). In terms of operation time, UBE group had the longest operation time (129.67 ±30.56 min), and OPD group had the shortest operation time (78.73 ± 11.80 min), with statistical difference (P<0.05). Conclusions: In terms of perioperative blood loss, the PEID group was more minimally invasive than the UBE and OPD groups. Compared with OPD group, UBE group was less invasive, but did not significantly reduce the amount of hidden blood loss after surgery. The clinician should choose the appropriate surgical plan according to the actual situation of the patient to ensure the efficacy and safety of the operation.
Keywords: Perioperative blood loss, Percutaneous endoscopic interlaminar discectomy, Unilateral biportal endoscopic, Open fenestration discectomy, Lumbar disc herniation, Hidden blood loss
Received: 26 Dec 2024; Accepted: 22 May 2025.
Copyright: © 2025 Wang, Guo, Song, Tang, Guo and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Liren Wang, Department of Orthopaedics, The Third Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.