SYSTEMATIC REVIEW article
Front. Neurol.
Sec. Dementia and Neurodegenerative Diseases
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1571361
Evaluating the Clinical Evidence of TCM in Alzheimer's Disease: An Evidence Map Perspective
Provisionally accepted
Shuqi Cui1
Yongli Zhao1Xiaowen Wang1Yingzi Huang1Jiaxi Ye1Ziyong Deng1Yanjiang Li1Hui Qin2Li Wang2Kaihua Wang2Guangshan Zheng2
Qin Qijing2*- 1Guangxi Traditional Chinese Medical University, Nanning, Guangxi Zhuang Region, China
- 2Guangxi International Zhuang Medical Hospital, Nanning, Guangxi Zhuang Region, China
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• This review elucidates the current evidence base for the treatment of Alzheimer's disease (AD) with Traditional Chinese Medicine (TCM).• The clinical studies included generally feature relatively small sample sizes. • A majority of these studies inadequately reflect the principles of syndrome differentiation and treatment, which are fundamental to TCM.• While TCM appears to hold potential for the treatment of AD, the overall quality of research in this area necessitates substantial improvement.
Keywords: Traditional Chinese Medicine, Alzheimer's disease, randomized controlled trials, Meta-analysis, evidence map
Received: 05 Feb 2025; Accepted: 06 Aug 2025.
Copyright: © 2025 Cui, Zhao, Wang, Huang, Ye, Deng, Li, Qin, Wang, Wang, Zheng and Qijing. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Qin Qijing, Guangxi International Zhuang Medical Hospital, Nanning, Guangxi Zhuang Region, China
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