ORIGINAL RESEARCH article
Front. Neurol.
Sec. Multiple Sclerosis and Neuroimmunology
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1587804
Neuropsychiatric Disorders among Ecuadorian patients with multiple sclerosis and neuromyelitis optica spectrum disorder
Provisionally accepted
- 1Hospital Carlos Andrade Marin (HCAM), Quito, Ecuador
- 2Pontificia Universidad Católica del Ecuador, Quito, Pichincha, Ecuador
- 3Central University of Ecuador, Quito, Pichincha, Ecuador
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Materials and methods: It is a cross-sectional study, 151 patients were included, 117 patients with MS and 34 patients with NMOSD. Information was obtained by collecting data from records of the patients. In order to establish the diagnoses of anxiety and depression, the Hamilton Depression Rating Scale (HDRS) and the Beck Depression Inventory (BDI) scales were completed. Results: MS and NMOSD were frequent in female sex and mestizo ethnicity. The psychiatric disorders were frequent in both diseases (70.9% in MS and 85% in NMOSD), the most frequent pathologies were anxiety and depression. We found low frequency of attempted suicide. Anxiety and depression were present in patients between 41 and 50 years of age. There is not a correlation between the severity of anxiety and depression with age and disability. Conclusion: It is the first Ecuadorian study in which we established a high prevalence of anxiety and depression in MS and NMOSD patients, the severity of both disease was not related with age and disability.
Keywords: Conceptualization, methodology, Software. Merino Patricio: Data curation, Writing-Original draft preparation. Jimbo Ruth: Visualization, Investigation. Correa Patricio: Supervision. Jimbo Ruth: Software, Validation. Merino Patricio, Jorge Pilco: Writing-Reviewing and Editing Multiple Sclerosis, Optical neuromyelitis
Received: 05 Mar 2025; Accepted: 26 Jun 2025.
Copyright: © 2025 CORREA-DIAZ, Jimbo, Romero and Merino. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: EDGAR PATRICIO CORREA-DIAZ, Hospital Carlos Andrade Marin (HCAM), Quito, Ecuador
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