ORIGINAL RESEARCH article
Front. Neurol.
Sec. Neuroepidemiology
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1594166
Global, regional, and national burden of intracerebral hemorrhage and attributable risk factors in youths and young adults, 1990-2021: a statistical analysis of incidence, mortality and DALYs
Provisionally accepted
- 1First Affiliated Hospital of Wannan Medical College, Wuhu, China
- 2Second People’s Hospital of Lu’an City, Lu'an, Anhui Province, China
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Intracerebral hemorrhage (ICH) remains a leading contributor to mortality and long-term disability worldwide. This study aims to report global trends in the incidence, mortality and disability-adjusted life years (DALYs) of ICH among youths and young adults from 1990 to 2021.This study analyzed ICH incidence, mortality, and DALYs in youth and young adults aged 15-39 years using data from the Global Burden of Disease (GBD) database. Rates for incidence, mortality, and DALYs were calculated per 100,000 population with 95% uncertainty intervals (UIs). Data from 204 countries and territories were stratified by age, sex, and location. Temporal trends were assessed through Joinpoint regression models to compute annual percent change (APC) and log-transformed linear regression models to estimate the average annual percentage change (EAPC).
Keywords: intracerebral hemorrhage, Global burden of disease, Incidence, Mortality, sociodemographic index
Received: 15 Mar 2025; Accepted: 14 Aug 2025.
Copyright: © 2025 Rui, Wu, Huang and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yuanyuan Rui, First Affiliated Hospital of Wannan Medical College, Wuhu, China
Qian Li, First Affiliated Hospital of Wannan Medical College, Wuhu, China
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