ORIGINAL RESEARCH article
Front. Neurol.
Sec. Headache and Neurogenic Pain
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1611447
The efficacy and prognosis analysis of short-term spinal cord stimulation in the treatment of zoster-associated pain: a retrospective study
Provisionally accepted
- 1Third Hospital of Shanxi Medical College, Taiyuan, Shanxi Province, China
- 2Shanxi Bethune Hospital, Shanxi Medical University, Taiyuan, Shanxi Province, China
- 3Second Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China
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Zoster-associated pain (ZAP) is the most common and intractable complication in the clinical setting when patients with herpes zoster (HZ) seek medical treatment. Short-term spinal cord stimulation (stSCS) has been validated as an effective means to relieve ZAP. However, in the existing literature, there is a paucity of comprehensive reports elaborating on the risk factors that impact its treatment efficacy. Objective: This study aimed to evaluate the clinical efficacy of stSCS in the treatment of ZAP, and to analyze the risk factors that influence the treatment efficacy. Methods: Clinical data of patients diagnosed with ZAP and who underwent stSCS surgery in the Pain Department of Shanxi Bethune Hospital from January 2020 to December 2023 were collected. A retrospective analysis was performed to evaluate their clinical efficacy. Principal component analysis(PCA) was utilized to screen potential factors influencing the efficacy, and Logistic regression was employed to establish a predictive model. The accuracy of the model was assessed through the Receiver Operating Characteristic (ROC) curve and the C-index.Results: A total of 98 patients were enrolled in this study. After stSCS treatment, the visual analogue scale (VAS) scores of pain were significantly reduced, the sleep quality of patients was improved, and the dosage of analgesic drugs was markedly decreased compared with that before treatment . The results of multivariate Logistic regression analysis indicated that age(odds ratio [
Keywords: Herpes Zoster, Zoster-associated pain, postherpetic neuralgia, Short-term spinal cord stimulation, clinical efficacy, Risk factors
Received: 14 Apr 2025; Accepted: 30 Jun 2025.
Copyright: © 2025 Wang, Gao, Yu, Yang, Zhang and Huo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jianzhong Huo, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China
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