REVIEW article
Front. Neurol.
Sec. Endovascular and Interventional Neurology
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1622630
This article is part of the Research TopicAdvances in the Understanding, Diagnosis, and Management of Intracranial and Extracranial Arterial DissectionsView all 11 articles
Middle Cerebral Artery Dissection: Pathophysiology, Diagnosis, and Therapeutic Options
Provisionally accepted
- 1Wuhan University, Wuhan, China
- 2Zhongnan Hospital, Wuhan, China
- 3Department of Cardiology, Wuhan University of Science & Technology, Hanyang Hospital, Wuhan 430050, Hubei, China, Wuhan, China
- 4Department of Neurology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China
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Middle cerebral artery dissection (MCAD) is a rare cerebrovascular disorder that can lead to ischemic stroke or hemorrhagic events. Although its exact incidence remains unclear, the detection rate of MCAD has increased in recent years with advancements in imaging technology. Based on a systematic literature review of MEDLINE/PubMed, the Cochrane Library, Web of Science, and EMBASE, combined with the latest guidelines on intracranial artery diseases and stroke management, this article comprehensively reviews the pathophysiological mechanisms, imaging characteristics, and treatment strategies for MCAD.
Keywords: Middle cerebral artery dissection, Risk factors, pathophysiology, Imaging characteristics, Treatment
Received: 04 May 2025; Accepted: 21 Jul 2025.
Copyright: © 2025 Yao, Yang and Yan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Nao Yan, Department of Neurology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China
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