ORIGINAL RESEARCH article
Front. Neurol.
Sec. Headache and Neurogenic Pain
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1622882
This article is part of the Research TopicThe association between the nervous system and the stomatognathic system: from etiology to diagnosis and treatment of orofacial painView all 9 articles
Pain experience and behavior management: efficacy of photobiomodulation as an adjunct to local anesthesia in MIH patients -a randomized split-mouth clinical study
Provisionally accepted
- Poznan University of Medical Sciences, Poznań, Poland
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Background: Pain management in children with Molar-Incisor Hypomineralization (MIH) poses challenges for pediatric dentists. MIH affects the enamel of the first permanent molars and incisors, increasing the risk of cavities, hypersensitivity, and making anesthesia and dental treatments more difficult. Children with MIH often experience dental fear, necessitating effective pain management techniques. Photobiomodulation (PBM) has potential analgesic benefits in dentistry but requires further evaluation for its effectiveness in MIH cases.Aim: This study aimed to assess the impact of photobiomodulation on pain control in maxillary permanent molars affected by MIH.Methods: In our randomized split-mouth clinical study, 45 participants (25 males, 20 females) aged 7 to 15 years, with both maxillary molars affected by MIH, were assigned to either the intervention group (PBM plus standard anesthesia, n=45 teeth) or the control group (standard anesthesia alone, n=45 teeth). PBM parameters included a power of 100 mW, a wavelength of 635 nm, energy of 6 J, fluence of 12 J/cm², and a duration of 60 seconds. Pain perception, anesthesia commencement, and its extension time were measured and analyzed using SPSS version 23.0 (p < 0.05).Results: The PBM group reported significantly lower subjective pain (mean VAS 2 [1-5]) compared to the control group (6 [2-8]), p < 0.001. FLACC scale scores were also lower in the intervention group ( 3 [1-5]) compared to the control group (7 [5-8]), p < 0.001. The PBM group showed a lower heart rate (84.6 bpm ± 6.1) compared to the control (113.2 bpm ± 6.1), p < 0.001. Additionally, the anesthesia developed faster in the PBM group (mean: 3.6 ± 0.9 minutes) compared to the control (6.1 ± 0.8 minutes, p < 0.001), and the anesthetic effect persisted longer (70.2 ± 3.9 minutes vs. 50.7 ± 8.9 minutes, p < 0.001).anesthesia in maxillary molars affected by MIH by diminishing pain experience and enhancing anesthesia effects, providing a promising approach for pain control in children.
Keywords: Dental pain, Pain Management, molar incisor hypomineralization, photobiomodulation, Local anesthesia
Received: 04 May 2025; Accepted: 28 Jul 2025.
Copyright: © 2025 OLSZEWSKA, Roszak, Szymczak, Paszyńska and Czajka -Jakubowska. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: ANETA OLSZEWSKA, Poznan University of Medical Sciences, Poznań, Poland
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