MINI REVIEW article
Front. Neurol.
Sec. Neuro-Ophthalmology
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1623798
This article is part of the Research TopicAdvances in Understanding Visual Disorders Linked to Cortical DysfunctionView all 4 articles
Anterograde Degeneration Along the Visual Pathway Following Optic Nerve Injury: A Review
Provisionally accepted
- University of Liège, Liège, Belgium
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The aim of this paper is to review anterograde degeneration throughout the anterior visual pathway, particularly in the optic tracts, the lateral geniculate nucleus, the optic radiations and the visual cortex, following optic nerve injury. Both structural and neuroimaging findings are considered in various diseases, such as optic neuritis and glaucoma. Magnetic resonance imaging findings help localize the specific brain regions where these changes can be observed.Furthermore, particular attention is given to the relationship between cortical atrophy and the location of the associated visual field defect.
Keywords: Anterograde degeneration, optic neuropathy, Multiple Sclerosis, Leber hereditary optic neuropathy, Amblyopia
Received: 06 May 2025; Accepted: 28 Jul 2025.
Copyright: © 2025 Chapelle. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Anne-Catherine Chapelle, University of Liège, Liège, Belgium
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