ORIGINAL RESEARCH article
Front. Neurol.
Sec. Endovascular and Interventional Neurology
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1625480
The correlation analysis between preoperative cerebral small vessel disease and carotid plaque echo characteristics
Provisionally accepted
- Xiamen Cardiovascular Hospital Xiamen University, Xiamen, China
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Purpose: This study explores the correlation between carotid plaques and cerebral small vessel disease (CSVD). Method: A total of 167 patients were divided into CSVD (n=119) and Non-CSVD (n=48) groups. Various clinical variables, including body mass index (BMI), coronary artery disease, hypertension, and carotid plaque echo characteristics, were evaluated using multivariate logistic regression analysis. Results: The analysis revealed that carotid isoechoic plaques (OR = 2.139, 95% CI 1.421–3.219, P < 0.001) and hypoechoic plaques (OR = 1.687, 95% CI 1.206–2.359, P = 0.002) are independent risk factors for CSVD. Other variables such as BMI, coronary artery disease, hypertension, and hyperlipidemia did not reach statistical significance. Conclusion: The presence of carotid isoechoic and hypoechoic plaques significantly increases the risk of CSVD, highlighting the importance of carotid imaging in assessing stroke risk and guiding clinical management.
Keywords: carotid plaque, Cerebral small vessel disease, ultrasound, Stroke, ultrasound imaging
Received: 09 May 2025; Accepted: 04 Sep 2025.
Copyright: © 2025 Zhou, Yan, Guo, Huang and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yanqing Zhou, Xiamen Cardiovascular Hospital Xiamen University, Xiamen, China
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