ORIGINAL RESEARCH article
Front. Neurol.
Sec. Neurocritical and Neurohospitalist Care
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1642148
This article is part of the Research TopicComprehensive Approaches to the Management of Chronic Subdural Hematoma: Integrating Surgical and Molecular InsightsView all articles
Synergistic Effects of Hyperbaric Oxygen Therapy Combined with MPNFS Nursing Model on Neurological Recovery and Recurrence Prevention After Chronic Subdural Hematoma Surgery
Provisionally accepted
- Changde Hospital, Xiangya School of Medicine, Central South University（The first people’s hospital of Changde city), Changde, China
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Background: Chronic subdural hematoma (CSDH) has high postoperative recurrence rates. This study investigates the effects of hyperbaric oxygen therapy (HBOT) combined with Medical-Psychosocial-Nursing Functional Support (MPNFS) on functional recovery and recurrence prevention in CSDH patients, and establishes a recurrence prediction model. Methods: A total of 184 CSDH patients undergoing burr hole drainage were randomized into a control group and an observation group (HBOT + MPNFS). Neurological (NIHSS), motor (Fugl-Meyer Assessment), and quality-of-life (SF-36) outcomes were assessed preoperatively and at 1-month postoperatively. Complications and 6-month recurrence rates were recorded. Univariate/multivariate logistic regression identified recurrence risk factors, with ROC analysis evaluating predictive accuracy. Results: The observation group showed superior 1-month outcomes: lower NIHSS scores (t = 4.94, P < 0.001), higher FMA and SF-36 scores (P < 0.01). Complication and recurrence rates were significantly reduced (P < 0.05). Independent recurrence predictors included brain atrophy (OR = 2.877), poor brain reexpansion (OR = 3.165), preoperative hematoma width ≥ 20 mm (OR = 2.782), and absence of combined intervention (OR = 2.842). The multifactorial model achieved an AUC of 0.7862, indicating robust predictive efficacy. Conclusion: HBOT combined with MPNFS enhances neurological/motor recovery, improves quality of life, and reduces complications/recurrence in postoperative CSDH patients.
Keywords: chronic subdural hematoma, hyperbaric oxygen therapy, MPNFS nursing model, neurological recovery, recurrence prediction
Received: 06 Jun 2025; Accepted: 28 Aug 2025.
Copyright: © 2025 Xie, Yang, Jiang, Liu and Gao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yan Gao, Changde Hospital, Xiangya School of Medicine, Central South University（The first people’s hospital of Changde city), Changde, China
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