ORIGINAL RESEARCH article
Front. Neurol.
Sec. Endovascular and Interventional Neurology
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1646081
Efficacy and safety of successful mechanical thrombectomy in elderly patients with anterior circulation large vessel occlusion acute ischemic stroke
Provisionally accepted
Wensheng Zhang1
Wen Lin2Yangchun Wen1Haiping Lan1Minzhen Zhu1Xiaojing Zhong1*Weifang Xing1*Zhenqin Jiang1*- 1Heyuan People's Hospital, Heyuan, China
- 2Guangzhou University of Traditional Chinese Medicine Maoming Hospital, Maoming, China
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Objective: To explore the efficacy and safety of successful mechanical thrombectomy (MT) in elderly patients with anterior circulation large vessel occlusion acute ischemic stroke (AIS).A retrospective analysis was conducted on 437 patients admitted to our hospital from January 2019 to November 2023 who received successful MT because of anterior circulation large vessel occlusion AIS. They were divided into an elderly group (age ≥ 80 years old) and a young group (age<80 years old). Their clinical data were analyzed.Results: There were 61 cases in the elderly group and 376 cases in the young group.Before and after propensity score matching analysis, there was no significant difference in any type of cerebral hemorrhage, cerebral hernia, futile recanalization and all-cause mortality between two groups of patients with a p value greater than 0.05.The incidence of any type of cerebral hemorrhage, cerebral hernia, futile recanalization and all-cause mortality in elderly patients with anterior circulation large vessel occlusion AIS was similar to that in young patients. Compared to young patients, MT is also effective and safe in elderly patients.
Keywords: anterior circulation, Large vessel occlusion, Acute ischemic stroke, advanced age, Mechanical thrombectomy
Received: 12 Jun 2025; Accepted: 19 Aug 2025.
Copyright: © 2025 Zhang, Lin, Wen, Lan, Zhu, Zhong, Xing and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xiaojing Zhong, Heyuan People's Hospital, Heyuan, China
Weifang Xing, Heyuan People's Hospital, Heyuan, China
Zhenqin Jiang, Heyuan People's Hospital, Heyuan, China
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