Your new experience awaits. Try the new design now and help us make it even better

REVIEW article

Front. Neurol.

Sec. Endovascular and Interventional Neurology

Research Progress on Risk Factors for In-Stent Restenosis Following Cerebrovascular Stent Implantation

Provisionally accepted
Haobo  GaoHaobo GaoHifsa  BibiHifsa BibiHongtu  TanHongtu TanYiwei  ZhangYiwei ZhangGuofang  YangGuofang YangJiabing  WangJiabing WangTao  WuTao Wu*
  • Henan University of Chinese Medicine, Zhengzhou, China

The final, formatted version of the article will be published soon.

Transient ischemic attack or ischemic stroke within 6 months is is frequently associated with severe carotid stenosis. . Carotid stent implantation is a widely employed treatment, but in-stent restenosis (ISR) is a dangerous postoperative complication. Many factors cause in-stent restenosis. Previous studies have indicated that stent type, drug use, patient-specific risk factors, levels of various factors in the patient's body, surgical procedures, and vascular physiological anatomy can all contribute to its occurrence. This review summarizes the key risk factors for ISR following CAS and briefly discusses related findings in intracranial artery stenting, aiming to inform clinical decision-making in neurointerventional practice.

Keywords: Stents, Carotid Stenosis, Neointima, Risk factors, Diabetes Mellitus

Received: 05 Jul 2025; Accepted: 27 Oct 2025.

Copyright: © 2025 Gao, Bibi, Tan, Zhang, Yang, Wang and Wu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Tao Wu, wt13592127512@126.com

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.