ORIGINAL RESEARCH article
Front. Neurol.
Sec. Headache and Neurogenic Pain
This article is part of the Research TopicThe association between the nervous system and the stomatognathic system: from etiology to diagnosis and treatment of orofacial painView all 10 articles
Impact of Low-Level Laser Therapy on Orthodontic Pain
Provisionally accepted
- 1Department of Maxillofacial Orthopaedics and Orthodontics, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Torun, Poland, Bydgoszcz, Poland
- 2Pomeranian Medical University, Szczecin, Poland
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Pain is a primary deterrent to patient compliance in orthodontics. While pharmacological options exist, their systemic side effects warrant exploration of non-invasive alternatives. This study introduces Low-Level Laser Therapy (LLLT) as a localized, non-pharmacological intervention and evaluates its efficacy in mitigating pain during the critical initial phase of fixed appliance treatment. Methods: In this prospective controlled study, 60 patients (aged14.6-37.1 years) were randomized into an LLLT group (n=20) and a control group (n=40). The LLLT group received daily photobiomodulation (670 nm, 4–6J/cm²) for five consecutive days post-appliance placement. Pain was assessed daily using the Visual Analogue Scale (VAS), Laitinen Scale, and Verbal Rating Scale (VRS). Oral hygiene was evaluated using the Approximal Plaque Index (API). Results: LLLT significantly reduced pain perception. Pain peaked on day 2 for both groups, but the VAS score was lower in the LLLT group (4.35) than the control group (5.30). By day 4, the difference was highly significant (LLLT: 2.05 vs. Control:3.77; p < 0.0014). Furthermore, the LLLT group demonstrated significantly better oral hygiene, with a lower increase in API scores from T0 to T5 compared to the control group (p < 0.0003). Conclusion & Application: LLLT is an effective and safe modality for reducing acute orthodontic pain. Its localized action, absence of systemic side effects, and positive influence on oral hygiene make it available clinical tool for improving patient comfort and compliance during orthodontic therapy. This study provides strong evidence supporting the integration of LLLT into routine orthodontic practice.
Keywords: Pain, Orthodontic Appliances, low- level light therapy, Low-level laser therapy, LLLT, Pain Management, Pain Measurement, Fixed appliance
Received: 15 Jul 2025; Accepted: 24 Oct 2025.
Copyright: © 2025 Jagla, Bielawska-Victorini and Woźniak. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Sylwia Jagla, sylwia.jagla@gmail.com
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