SYSTEMATIC REVIEW article
Front. Neurol.
Sec. Experimental Therapeutics
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1697481
The Efficacy and Safety of Acupuncture for Parkinson's Disease Insomnia: A Systematic Review and Meta-Analysis
Provisionally accepted
- Tai’an City Central Hospital of Qingdao university, Tai’an, China
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Background: Insomnia is a common comorbid symptom in Parkinson's disease (PD) patients, significantly impairing their quality of life. Acupuncture is widely applied in treating PD insomnia, yet relevant evidence remains fragmented. Objective: To investigate the efficacy of acupuncture in improving PD insomnia through systematic review and meta-analysis, evaluating its clinical effectiveness and safety. Methods: Eight electronic databases were searched: PubMed, Cochrane Library, Embase, Web of Science, China National Knowledge Infrastructure (CNKI), VIP Data Platform, Wanfang Data Knowledge Service Platform, and China Biomedical Literature Service System. References from relevant literature and clinical trial registries were manually searched for randomised controlled trials (RCTs) on acupuncture for PD insomnia. Studies were screened against inclusion and exclusion criteria, relevant data extracted, and meta-analysis conducted using RevMan 5.4 software. Results: Eleven studies involving 800 patients were included. Meta-analysis revealed that acupuncture effectively improved PSQI (MD = −2.87, 95% CI: −4.28 to −1.46, P < 0.0001) and PDSS (MD = 7.96, 95% CI: 5.55 to 10.37, P < 0.00001), demonstrating superior efficacy compared to the control group (MD = 6.64, 95% CI: 3.47 to 12.69, P < 0.00001). Conclusion: Acupuncture effectively improves PSQI and PDSS scores in patients with PD insomnia and exhibits superior efficacy over the control group. However, due to limitations, further details could not be explored.
Keywords: Acupuncture, Parkinson's disease, insomnia, Systematic review, Meta-analysis
Received: 02 Sep 2025; Accepted: 21 Oct 2025.
Copyright: © 2025 Gu, Liang, Han, Yin and Zheng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Zuncheng Zheng, zhengzc1965@126.com
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