ORIGINAL RESEARCH article
Front. Neurol.
Sec. Neuro-Oncology and Neurosurgical Oncology
This article is part of the Research TopicImproving neurosurgical precision: leveraging technology for enhanced visualization and navigation of complex neuroanatomyView all 12 articles
Technical Innovation: Analysis of the Utilization of Laser Navigation-Assisted Minimally Invasive Surgery for Basal Ganglia Hemorrhage in Primary Hospitals
Provisionally accepted
- 1Department of Neurosurgery, Binzhou Medical University Hospital, Binzhou, China
- 2Department of Neurosurgery, Xiamen Key Laboratory of Brain Center, School of Medicine, Xiamen University, The First Affiliated Hospital of Xiamen University, Xiamen, China
- 3Xiamen University School of Medicine, Xiamen, China
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Abstract Background: Spontaneous basal ganglia hemorrhage (sBGH) is a critical condition with various surgical treatment options, including traditional craniotomy, endoscopic evacuation, and minimally invasive surgery (MIS). Laser navigation-assisted puncture is a novel technique integrated with MIS, offering real-time positioning. This study aims to evaluate the clinical outcomes and neurological effects of laser navigation-assisted puncture, endoscopic evacuation, and traditional craniotomy in sBGH patients. Methods: This retrospective, single-center, nested case-control (NCC) study included 75 adults with sBGH, treated between June 2021 and June 2023. The patients were categorized into three groups based on their treatment methods: laser navigation-assisted puncture with urokinase injection, endoscopic evacuation, and traditional craniotomy. Multivariable logistic regression was used to assess the impact of surgical approaches on short-term surgical outcomes and neurological prognosis. Results: Laser navigation-assisted MIS significantly reduced operation time compared to both endoscopic evacuation (P = 0.000016) and traditional craniotomy (P = 0.000006). The laser navigation-assisted MIS group and endoscopic evacuation group had fewer complications than the craniotomy group (P = 0.011). However, hematoma clearance rates showed no significant differences across groups. The surgical method did not significantly influence the prognosis, as assessed by the Glasgow Outcome Scale (GOS) and the National Institutes of Health Stroke Scale (NIHSS). Conclusion: Laser navigation-assisted hematoma puncture with urokinase injection is a practical and effective treatment for sBGH, offering benefits such as reduced surgical time and lower complication rates compared to traditional craniotomy. While no significant differences were observed in patient prognosis, this study supports the efficacy of MIS techniques in the management of sBGH.
Keywords: endoscopic hematoma evacuation, Laser Navigation-Assisted Hematoma Puncture, minimally invasive surgery, Spontaneous Basal Ganglia Hemorrhage, Traditional craniotomy
Received: 23 Sep 2025; Accepted: 08 Dec 2025.
Copyright: © 2025 Wang, Yuan, Liu, Liu and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Zefu Li
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