EDITORIAL article
Front. Neurol.
Sec. Applied Neuroimaging
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1714644
This article is part of the Research TopicApplied Neuroimaging for the Diagnosis and Prognosis of Cerebrovascular DiseaseView all 15 articles
Editoral: Applied Neuroimaging for the Diagnosis and Prognosis of Cerebrovascular Disease
Provisionally accepted
- 1Characteristic Medical Center of Chinese People's Armed Police Force, Tianjin, China
- 2University of Nebraska Medical Center, Omaha, United States
- 35th Medical Center of Chinese PLA General Hospital, Beijing, China
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anatomical structure and function of the brain, providing important evidence for the diagnosis and treatment of cerebrovascular diseases. This research topic summarizes fourteen recent original research studies that explore the application of advanced imaging techniques in evaluating and predicting outcomes of key neurological disorders, including intracranial arterial disease (ICAD)-related ischemic stroke, acute ischemic stroke (AIS) post-mechanical thrombectomy, transient ischemic attack (TIA), aneurysmal subarachnoid hemorrhage (aSAH), heart failure, etc. The studies highlight how imaging modalities such as computed tomography (CT), multimodal magnetic resonance imaging (MRI), high-resolution vessel wall imaging (HR-VWI), and arterial spin labeling (ASL) provide critical insights into disease pathophysiology, temporal dynamics, and prognosis, offering valuable tools for clinical decisionmaking.CT and CTA are foundational in vascular neurological assessments due to their speed and accessibility. In extracranial carotid artery disease, the ANTIQUE study (Pakizer et al., 2025) used CTA to classify carotid plaque calcification into spotty (<3mm) and large (>3mm) types. It found that spotty calcification correlated with male sex and heavy smoking (p = 0.014), while large calcification was associated with older age, coronary heart disease, and atrial fibrillation (p = 0.025). In acute stroke, CTA assesses stenosis severity and plaque morphology. Chen et al. showed that acute stroke patients had higher systolic blood pressure, thicker plaques, and more severe stenosis on CTA than non -acute patients. CTA -derived perivascular fat density (PFD) was a strong predictor of acute ischemia, with symptomatic -side PFD Most patients were women (73%, average age 46), with high prevalence of chronic fatigue (90%), headache (57%), and sleep disorders (51%). Brain MRI showed lesions in 72%, spine MRI in 16%, but no significant correlation between lesions and fatigue (p=0.815) or headache (p=0.178). This suggests T2-hyperintense lesions may not drive these PCS symptoms.
Keywords: Neuroimaging, cerebrovascular diseases, diagnosis, prognosis, Stroke
Received: 28 Sep 2025; Accepted: 29 Sep 2025.
Copyright: © 2025 Lu, Wang and Cai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Mingming Lu, andy_lu_ok@126.com
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