ORIGINAL RESEARCH article
Front. Surg.
Sec. Surgical Oncology
Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1477658
Efficacy and prognosis analysis of pulley traction-assisted endoscopic submucosal dissection with dental floss for early gastric cancer and precancerous lesions
Provisionally accepted
- 1Shanghai General Hospital, Shanghai, China
- 2Jiangwan Hospital of Hongkou District, Shanghai, China
- 3Shanghai Pudong New Area People's Hospital, Pudong, Shanghai Municipality, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Objective: To investigate the clinical efficacy of pulley traction-assisted endoscopic submucosal dissection (ESD) with dental floss in patients with early gastric cancer and precancerous lesions, and its impact on patient prognosis.Methods: Clinical data of 77 patients with early gastric cancer and precancerous lesions were retrospectively analyzed. The patients were divided into groups according to different treatment regimens; 38 patients in the control group underwent ESD, whereas 39 patients in the study group underwent pulley traction-assisted ESD with dental floss. Lesion resection status, perioperative indicators, gastrointestinal function indicators, complications, and recurrence were compared between the two groups.Results: The curative and en bloc resection rates in the study group were significantly higher than those in the control group, whereas the residual rate of basal lesions was significantly lower than that in the control group (P<0.05). The study group experienced less intraoperative bleeding and had a significantly shorter operative time, anal exhaust time, first eating time, and length of hospital stay (P<0.05). Three days postoperatively, motilin (MTL), gastrin (GAS), pepsinogen I (PG I), and pepsinogen II (PG II) levels were significantly reduced in both groups, with significantly higher levels in the study group (P<0.05). The incidence of complications in the study group was 7.69% (3/39), which was significantly lower than that in the control group (26.32 % (10/38); P<0.05). Three months postoperatively, the quality of life scores (FACT-G) in all aspects significantly increased in both groups, with the study group showing significantly higher scores (P<0.05). The recurrence rate at 12 months postoperatively in the study group (5.13%) was significantly lower than that in the control group (23.68%; P<0.05).Conclusion: Pulley traction-assisted ESD with dental floss is effective in treating early gastric cancer and precancerous lesions.
Keywords: gastric cancer, Dental floss traction, early stage, Precancerous lesions, Endoscopic Submucosal Dissection
Received: 08 Aug 2024; Accepted: 03 Jul 2025.
Copyright: © 2025 Luo, Tang, He, Shi and Chang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yunli Chang, Shanghai Pudong New Area People's Hospital, Pudong, Shanghai Municipality, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.