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CASE REPORT article

Front. Surg.

Sec. Neurosurgery

Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1537318

This article is part of the Research Topic10th Anniversary of Frontiers in Surgery: Celebrating Progress and Envisioning the Future of Multidisciplinary SurgeryView all 14 articles

Endoscopic Microvascular Decompression for Trigeminal Neuralgia in a Centenarian: A Landmark Case with 5-Year Follow-Up

Provisionally accepted
Xuhao  FangXuhao Fang*Feng  TangFeng TangDeng  YaoDeng YaoRenling  MaoRenling Mao
  • Huadong Hospital, Fudan University, Shanghai, China

The final, formatted version of the article will be published soon.

Background Endoscopic Microvascular Decompression (E-MVD) is a wellestablished effective treatment option for trigeminal neuralgia (TN). However, its application in ultra-elderly patients, particularly centenarians, has never been documented.Case Description: A centenarian with TN for five years presented to our hospital in January 2020. Her symptoms had progressively worsened over the preceding three months. Despite extreme age, her organ function remained relatively preserved based on comprehensive physical and laboratory examinations. E-MVD was performed, and the patient experienced immediate pain relief without any neurological dysfunction.During five years of follow-up, there was no recurrence of symptoms; the patient remains symptom-free at 105 years of age.This case study presents the successful use of E-MVD in a centenarian patient suffering from TN, highlighting its potential as a viable treatment option even in this advanced age group. Further studies are needed to confirm these findings and explore the generalizability of this approach.

Keywords: Trigeminal Neuralgia, centenarian, Microvascular decompression, Neuroendoscope, case report

Received: 30 Nov 2024; Accepted: 24 Jul 2025.

Copyright: © 2025 Fang, Tang, Yao and Mao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Xuhao Fang, Huadong Hospital, Fudan University, Shanghai, China

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