ORIGINAL RESEARCH article

Front. Surg.

Sec. Visceral Surgery

Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1564843

This article is part of the Research TopicRegenerative Liver SurgeryView all articles

Anticipating Postoperative Complications in Hepatobiliary Surgery: Procalcitonine as Predictive Factor

Provisionally accepted
Shouwen  ZhaoShouwen Zhao1Yuanyuan  SongYuanyuan Song1Le  ZhangLe Zhang2Sunan  ShiSunan Shi2Jie  LiJie Li2Yuping  MaYuping Ma1Yong  LiaoYong Liao1Zhongguang  ZhenZhongguang Zhen1*
  • 1Xingtai People's Hospital, Xingtai, China
  • 2Hebei Eye Hospital, Xingtai, China

The final, formatted version of the article will be published soon.

Background and aims: Few studies have indicated that procalcitonin has a potential role in anticipating postoperative complications of hepatic surgery. Here, we focused on validating the relationship between posthepatectomy and serum procalcitonin as short-term prognostic factors.Methods: Data from 52 patients who underwent hepatectomy (partial) due to hepatocellular carcinoma from June 2018 to July 2023 were enrolled to evaluate the risk factors related to posthepatectomy complications, especially post-hepatectomy liver failure and 30-day survival.Results: 52 patients were included in the study, and their data was analyzed for PCT. 21 showed raised PCT (>1ng/ml). Results showed a significant association of PCT with post-hepatectomy liver failure, and the same is associated with 30-day mortality in ICU-admitted patients.Elevated PCT levels in patients after hepatic surgery are associated with poor prognosis and could be used as a potential predictive factor.

Keywords: Procalcitonin, Hepatectomy, Postoperative Complications, liver failure prognostic factor., Liver Failure

Received: 22 Jan 2025; Accepted: 12 May 2025.

Copyright: © 2025 Zhao, Song, Zhang, Shi, Li, Ma, Liao and Zhen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Zhongguang Zhen, Xingtai People's Hospital, Xingtai, China

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