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REVIEW article

Front. Surg.

Sec. Orthopedic Surgery

Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1586187

This article is part of the Research TopicNew Advances in Prosthetic Surgery of Large JointsView all 8 articles

Comparison of Direct Anterior vs. Posterior Approach in Primary Total Hip Arthroplasty: A Systematic Review and Meta-Analysis on Enhanced Recovery After Surgery

Provisionally accepted
Wenqian  XuWenqian Xu1Jinjin  LaoJinjin Lao2Jinsong  LiuJinsong Liu1Zengrui  ZhangZengrui Zhang1Xiaoyu  WanXiaoyu Wan1Zhiguang  ChenZhiguang Chen1Xiaotao  HuangXiaotao Huang2Nan  ChenNan Chen1Yingxing  XuYingxing Xu1*
  • 1The First Affiliated Hospital of Kunming Medical University, Kunming, China
  • 2Cixi Integrated Traditional Chinese and Western Medicine Medical and Health Group, Cixi, China

The final, formatted version of the article will be published soon.

Purpose: This meta-analysis aimed to compare the direct anterior approach (DAA) and posterior approach (PA) for total hip arthroplasty (THA) within the context of enhanced recovery after surgery (ERAS).Methods: Studies comparing DAA and PA for THA were systematically retrieved from Pubmed, Embase, Web of Science, the Cochrane Library, and Google Scholar databases, covering the period from 2012 to 2024. A meta-analysis was conducted to compare the ERAS-related outcomes between DAA and PA for THA using RevMan 5.3 software, including surgical trauma, muscle damage, functional recovery, and complications. Heterogeneity was considered significant if I² > 50%, in which case a random effects model and subgroup analysis were applied. Continuous and dichotomous data were analyzed using 95% confidence intervals (CIs).Methodological quality and heterogeneity assessments were also conducted.Results: A total of 48 studies, including 46,367 hips (13,285 in the DAA group and 33,082 in the PA group), were included. Compared to PA, DAA was associated with significantly lower blood transfusion rates [6.62% vs 14.52%; odds ratio (OR) = 0.73; 95% CI: 0.59 -0.91; P < 0.005], shorter hospital stay [mean difference (MD) = -0.88 days; 95%

Keywords: Direct anterior approach, Posterior approach, Total hip arthroplasty, Enhanced recovery after surgery, meta analysis

Received: 02 Mar 2025; Accepted: 23 Jul 2025.

Copyright: © 2025 Xu, Lao, Liu, Zhang, Wan, Chen, Huang, Chen and Xu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Yingxing Xu, The First Affiliated Hospital of Kunming Medical University, Kunming, China

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