CASE REPORT article
Front. Surg.
Sec. Neurosurgery
Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1598308
Case Report: Cranial intradural chordoma following extradural spinal chordoma
Provisionally accepted
- 1Demiroglu Bilim University, Istanbul, Türkiye
- 2Maastricht University, Maastricht, Netherlands
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Chordomas are uncommon, locally invasive, and slow-growing neoplasms that originate from remnants of the primitive notochord. They account for approximately 1% of all intracranial tumors and are typically found in the sacrococcygeal region or at the skull base. Purely intradural intracranial chordomas are exceptionally rare, with only 67 cases documented to date, to the best of our knowledge. These tumors are generally situated near the midline. We present the case of a 67-yearold male who developed hemiparesis and hemihypoesthesia 6 years after undergoing surgery for a classical spinal chordoma that was purely extradural. Magnetic resonance imaging revealed a mass in the frontoparietal area, initially suggestive of an intra-axial tumor. However, intraoperative findings indicated that the lesion was extraaxial, and histopathological evaluation confirmed it as an intradural chordoma. As far as we are aware, this is the first reported case of a chordoma within the brain parenchyma away from the midline.
Keywords: intradural chordoma, Cranial chordoma, metastasis, brain parenchymal lesion, spinal chordoma
Received: 22 Mar 2025; Accepted: 04 Sep 2025.
Copyright: © 2025 Sarı, Akçakaya, Temel and Elmacı. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Mehmet Osman Akçakaya, Demiroglu Bilim University, Istanbul, 34394, Türkiye
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