ORIGINAL RESEARCH article
Front. Surg.
Sec. Vascular Surgery
Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1598354
Early outcomes of drug-coated balloon angioplasty and stent placement for the treatment of iliac artery lesions
Provisionally accepted
- Beijing Chaoyang Hospital, Capital Medical University, Beijing, Beijing Municipality, China
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The efficacy and safety of drug-coated balloons (DCBs) in the treatment of aortoiliac artery stenosis or occlusion remains poorly explored.A single-center retrospective cohort study of patients diagnosed with iliac artery stenosis or occlusion who received either iliac artery DCB angioplasty or stent implantation was conducted at our institution. The patients were followed up 6 and 12 months postoperatively. Lower limb computed tomography angiography was performed during the follow-up period. The primary endpoint of the study was the primary patency at 6 and 12 months. Both the clinical and follow-up data were analyzed.50 patients underwent DCB angioplasty, while 71 received stent implantation.Demographic and lesion characteristics were comparable between the two groups (P > 0.05). However, the balloon diameter used in the DCB group was significantly smaller (6.42 ± 0.80 mm vs. 7.39 ± 0.97 mm, P＜0.001). The primary patency values 6 and 12 months postoperatively were 84.2% and 80.7% for the DCB group and 96.1% and 89.6% for the stent group, respectively with no significant difference between the two groups (P=0.124). However, the 12-month patency in the common iliac artery segment for the DCB group was significantly lower than that for the stent group (75.0% vs. 97.3%, P=0.006). Univariate and multivariate logistic analyses did not identify any factors associated with long-term patency.Same as stents, DCBs maintained a favorable but lower patency rate across various calcification levels and different TASC Ⅱ classification in patients with aortoiliac artery stenosis or occlusion.
Keywords: atherosclerosis obliterans, Iliac Artery, Drug-coated balloon, stent, Endovascular Therapy
Received: 30 Mar 2025; Accepted: 17 Jun 2025.
Copyright: © 2025 Wen, Li, Jin and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jiahao Wen, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100001, Beijing Municipality, China
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