ORIGINAL RESEARCH article
Front. Surg.
Sec. Orthopedic Surgery
Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1606944
This article is part of the Research TopicNew Perspectives and Innovative Techniques in Contemporary Spine Surgery - Volume IIView all 9 articles
Visceral Fat: The Hidden Culprit Behind Thoracolumbar Surgery Infections
Provisionally accepted
- Department of Spinal Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, China
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Objective: This study aimed to explore the relationship between visceral fat area (VFA) and the risk of surgical site infection (SSI) after thoracolumbar posterior surgery. Methods: A retrospective analysis was conducted on 1,491 patients who had undergone posterior thoracolumbar surgery from January 1, 2022, through May 30, 2023. Inclusion criteria were age ≥ 18 years, undergoing thoracolumbar posterior surgery, and having complete clinical data with a follow-up duration exceeding 1 year. Exclusion criteria included minimally invasive surgery, preoperative infections, traumatic skin injuries, combined tumors, and patients with long-term steroid use or immune system diseases. VFA was measured using CT scans, and patients were categorized based on VFA ≥100 cm² as having visceral fat obesity. The incidence of SSI was assessed according to the CDC criteria. Logistic regression analysis was used to identify risk factors for SSI. Results: The incidence of SSI was 2.4% (36 out of 1,491 patients). Multivariate logistic regression analysis showed that VFA was the most significant predictor of SSI (P<0.001; Exp(B)=1.026; 95% CI, 1.013-1.040), indicating a 2.6% increased infection risk per 1 cm² increase in VFA. Other significant risk factors included BMI (P=0.024; Exp(B)=1.138; 95% CI, 1.018-1.273). Patients with visceral fat obesity had a significantly higher infection rate (5.7% vs. 1.2%, P<0.001). Conclusion: VFA is a significant risk factor for SSI following thoracolumbar posterior surgery. Preoperative assessment of VFA can help identify high-risk patients and guide preventive measures to reduce SSI incidence and improve surgical outcomes.
Keywords: Visceral fat area (VFA), Surgical site infection (SSI), thoracolumbar surgery, Obesity, Infection risk factors
Received: 06 Apr 2025; Accepted: 26 Jun 2025.
Copyright: © 2025 Su, Wang, ;i, An, Sun, Cui and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Di Zhang, Department of Spinal Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, China
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