ORIGINAL RESEARCH article
Front. Surg.
Sec. Genitourinary Surgery and Interventions
Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1614661
Laparoscopic Nephrectomy for Giant Ruptured Renal Angiomyolipoma in Tuberous Sclerosis: Case Report and Literature Review
Provisionally accepted
- Mianyang Central Hospital, Mianyang, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Tuberous sclerosis complex (TSC) is an autosomal dominant disease affecting multiple organs and systems throughout the body. The rupture and bleeding of TSC-associated renal angiomyolipoma (RAML) are the most common causes of death in adults with TSC. Clinically, interventional embolization and open surgery remain the standard treatment options for RAML, with laparoscopic procedures being comparatively less utilized. This article details the management of a 59-year-old male with TSC who presented with spontaneous rupture and hemorrhage of a large right renal RAML measuring over 15 cm in diameter. A laparoscopic right nephrectomy was successfully performed. The diagnostic and therapeutic management of this case is discussed with a review of the relevant literature.
Keywords: tuberous sclerosis complex, renal angiomyolipoma, laparoscopic unilateral nephrectomy, case report, literature review
Received: 01 May 2025; Accepted: 30 Sep 2025.
Copyright: © 2025 Cao, Liao, Yan, He, Wang, wang, Zhang, Wang and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Jianjun Wang, wangjianjunmch@163.com
Shichun Jiang, 372239819@qq.com
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.