ORIGINAL RESEARCH article
Front. Surg.
Sec. Colorectal and Proctological Surgery
Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1624266
Outcomes of high BMI colorectal cancer patients with natural orifice specimen extraction surgery: a propensity-score matching study
Provisionally accepted
- 1The Second Affiliated Hospital of Harbin Medical University, Harbin, China
- 2Bashkir State Medical University, Republic of Bashkortostan, Russia
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Natural orifice specimen extraction surgery (NOSES) is widely used for colorectal cancer. However, there is limited study regarding the outcomes of patients with high BMI who undergo NOSES surgery for colorectal cancer.This retrospective study included 251 patients (including 205 Non-High BMI and 46 High BMI patients) who underwent NOSES for colorectal cancer between January 2013 and December 2018. Outcomes related to surgery, anal function and long-term survisval were compared between the Non-High BMI and High BMI patients with the propensity-score matching (PSM) method. Age, gender, tumor location (sigmoid/rectum), preoperative CEA, CA199, T stage and N stage were considered as covariates for PSM.After matching, 44 patients in the Non-High BMI group and 44 patients in the High BMI group were eligible for analysis. No significant differences were observed between the groups in terms of operative time, blood loss, time to first flatus, time to first diet, postoperative hospital stays, positive margin, postoperative complication, conversion to open surgery and pathological outcomes (all P-value > 0.05). Besides, there was no significant difference for anal function 6 months after surgery between the two groups (P = 0.723). The overall survival (OS) and disease-free survival (DFS) for the Non-high BMI group were comparable to those for the High BMI group (P = 0.156 for OS, P = 0.266 for DFS).With careful preoperative evaluation, High-BMI patients can successfully undergo NOSES surgery and achieve favorable outcomes.
Keywords: colorectal cancer, Noses, BMI, outcomes, Surgery
Received: 07 May 2025; Accepted: 28 Jul 2025.
Copyright: © 2025 Zhang, Zhang, Li, Yu, Qi, Wang, Artur and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Ibatullin Artur, Bashkir State Medical University, Republic of Bashkortostan, Russia
Guiyu Wang, The Second Affiliated Hospital of Harbin Medical University, Harbin, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.