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ORIGINAL RESEARCH article

Front. Surg.

Sec. Pediatric Orthopedics

Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1633136

Effectiveness of curettage and bone grafting with and without Elastic Intramedullary Nailing in the Treatment of Simple Bone cyst in Children: A Meta-analysis

Provisionally accepted
Siyu  LiSiyu Li1Lintao  WangLintao Wang2Yanan  LiYanan Li2Shuai  LiShuai Li2Dan  WangDan Wang2Zhen  DongZhen Dong2*
  • 1Shandong Second Medical University, Weifang, China
  • 2Women and Children's Hospital Affiliated to Qingdao University, Qingdao, China

The final, formatted version of the article will be published soon.

Aim To systematically evaluate the effectiveness of curettage and bone grafting with and without elastic intramedullary nailing in the treatment of simple bone cyst in children by analyzing domestic and international literature. Methods Systematically search for literature comparing the efficacy of curettage and bone grafting with and without elastic intramedullary nailing in the treatment of simple bone cyst in children in databases such as Pubmed, Cochrane Library, Embase, CBM, CNKI, Wanfang, and VIP. Conduct quality assessment and data extraction of included literature and perform meta-analysis calculations using Stata12.0 software. Results Meta-analysis showed no heterogeneity (P=0.581, I²=0%). The cure rate was significantly higher in the EIN group (OR=2.66, 95%CI=1.48–4.77, P=0.001) and 81% lower refracture incidence (OR=0.19, 95%CI=0.04–0.87, P=0.032) versus curettage alone. Conclusion Curettage and bone grafting with elastic intramedullary nailing is superior to curettage and bone grafting alone for treating simple bone cysts, with lower postoperative refracture incidence. Although the latter may require only one surgery theoretically, refracture or recurrence could necessitate 2–3 additional surgeries.

Keywords: Simple bone cyst/ Unicameral bone cyst (SBC/ UBC), curettage and bonegrafting, Elastic intramedullary nailing, Meta-analysis, Children

Received: 05 Jun 2025; Accepted: 25 Sep 2025.

Copyright: © 2025 Li, Wang, Li, Li, Wang and Dong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Zhen Dong, 17657033497@163.com

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