REVIEW article
Front. Surg.
Sec. Vascular Surgery
Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1637121
This article is part of the Research TopicEnhanced Recovery After Vascular Surgery: State of the Art and Future PerspectivesView all 3 articles
Multidisciplinary protocols are an important part of enhanced recovery after major lower extremity amputation
Provisionally accepted
- University of California, San Francisco, San Francisco, United States
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Major lower extremity amputation (MLEA) remains a high-risk procedure with significant implications for patient morbidity, mortality, and long-term functional independence. Optimizing outcomes for this vulnerable population requires a comprehensive, multidisciplinary approach guided by evidence-based perioperative care pathways. Enhanced Recovery After Surgery (ERAS) protocols offer a structured framework to improve recovery trajectories by standardizing key elements of care. This review examines the application of ERAS principles to the MLEA population, synthesizing current literature on preoperative assessment and patient selection, multimodal analgesia, early mobilization strategies, and coordinated post-discharge planning. By integrating findings from consensus statements and pilot studies, we demonstrate how tailored ERAS-based multidisciplinary protocols can reduce complications, enhance functional recovery, and promote equity in outcomes. The development and implementation of such structured care pathways represent a critical step toward improving the standard of care for patients undergoing major lower extremity amputation.
Keywords: Vascular Surgery, CLTI, Major lower extremity amputation, Eras (enhanced recovery afer surgery), multidiscipliary team
Received: 28 May 2025; Accepted: 15 Sep 2025.
Copyright: © 2025 Campat and O'Banion. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Christian Campat, christian.campat@ucsf.edu
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