REVIEW article
Front. Surg.
Sec. Orthopedic Surgery
Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1640316
This article is part of the Research TopicDiagnosis and Treatment in Age-related musculoskeletal disordersView all 17 articles
Subchondral Insufficiency Fracture of the Knee:Progress in the Pathogenesis and Treatment
Provisionally accepted
- 1Zhejiang Chinese Medical University, Hangzhou, China
- 2First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, China
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Subchondral Insufficiency Fracture of the Knee (SIFK) is a disease with unclear pathogenesis and rapid progression, it is prone to developing end-stage osteoarthritis. Due to the lack of a definitive treatment strategy for SIFK in the clinic, knee replacement is often the preferred measure. However, in recent years, as the disease has become better understood, more and more effective treatments have been proposed, but there is a lack of summarization. Therefore, this article summarizes its pathogenesis and therapeutic advances.
Keywords: subchondral insufficiency fracture of the knee, Subchondral insufficiency fracture, Spontaneous osteonecrosis of the knee, Subchondral lesion, review
Received: 03 Jun 2025; Accepted: 30 Sep 2025.
Copyright: © 2025 Wang, Zhang, Pei, Yuan, Wang and He. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Bangjian He, hebangjian@163.com
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