REVIEW article
Front. Surg.
Sec. Orthopedic Surgery
This article is part of the Research TopicAdvancing Musculoskeletal Health: Bridging Basic and Clinical Research on Biomechanical Properties of Joints, Ligaments, Tendons, and Associated StructuresView all 13 articles
Tranexamic Acid in Arthroscopic Surgery: Efficacy, Safety, and Clinical Considerations
Provisionally accepted
- 1Hainan Vocational University of Science and Technology, Haikou, China
- 2Central Hospital Affiliated to Shenyang Medical College, Shenyang, China
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This study reviews the applications and effects of tranexamic acid in arthroscopic surgery. Bleeding during arthroscopic surgery is an important factor affecting surgical outcomes and postoperative recovery. Tranexamic acid is an anti fibrinolytic drug that can effectively inhibit fibrin degradation and may be helpful in reducing surgical bleeding and improving surgical field clarity. In this review, the pharmacological mechanism of tranexamic acid is first introduced, including its effect on the fibrinolytic system and its specific mechanism of action to reduce bleeding. Subsequently, the review describes the application of tranexamic acid in arthroscopic surgery, analyzes the safety of tranexamic acid in arthroscopic surgery, and related factors affecting the effectiveness of tranexamic in arthroscopic surgery. In addition, this review highlights future research directions regarding tranexamic acid in arthroscopic surgery. A comprehensive analysis of existing literature indicates that tranexamic acid has an impact on blood loss, pain, surgical time, surgical field clarity, and postoperative function during arthroscopic surgery. Therefore, the application of tranexamic acid in arthroscopic surgery has high clinical value and significance.
Keywords: Tranexamic Acid, Arthroscopic surgery, application, Safety, Blood loss
Received: 05 Aug 2025; Accepted: 31 Oct 2025.
Copyright: © 2025 Tian, Wang and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Wei Wang, wwbnwsvvip@163.com
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