ORIGINAL RESEARCH article
Front. Surg.
Sec. Genitourinary Surgery and Interventions
Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1680837
This article is part of the Research TopicInnovations in Treating Ureteral Strictures and Upper Urinary Tract IssuesView all 3 articles
Analysis of risk factors for ureteral stricture and tumor recurrence after transurethral resection of bladder tumor in paraureteral bladder cancer
Provisionally accepted
- Tsinghua University Yuquan Hospital, Beijing, China
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Background: This study explores the risk factors for ureteral stricture and tumor recurrence after transurethral resection of bladder tumor (TURBT) in patients with paraureteral bladder cancer, aiming to provide references for clinicians in their treatment practices. Methods: A retrospective analysis was conducted on 164 patients with paraureteral bladder cancer who underwent TURBT from April 2017 to July 2024, among whom 133 patients had complete clinical data and follow-up data. Univariate and multivariate logistic regression analyses were used to identify the risk factors for ureteral stricture and tumor recurrence after TURBT in paraureteral bladder cancer. Results: The incidence of ureteral stricture after TURBT in patients with paraureteral bladder cancer was 11.28% (15/133), and the recurrence rate of bladder cancer within 1 year after surgery was 21.80% (29/133). Multivariate logistic regression analysis showed that diabetes mellitus (p=0.021) and tumor diameter (p=0.002) were independent risk factors for ureteral stricture within 1 year after TURBT. Additionally, multivariate logistic regression analysis revealed that sex (p=0.021), diabetes mellitus (p=0.008), and pathological T stage (p=0.002) were independent risk factors for bladder tumor recurrence within 1 year after TURBT. Conclusion: Diabetes mellitus and tumor diameter are independent risk factors for ureteral stricture within 1 year after TURBT in patients with paraureteral bladder cancer. Sex, diabetes mellitus, and pathological T stage are independent risk factors for bladder tumor recurrence within 1 year after TURBT in these patients.
Keywords: TURBT, paraureteral bladder cancer, tumor recurrence, ureteral stricture, Diabetes Mellitus
Received: 06 Aug 2025; Accepted: 22 Sep 2025.
Copyright: © 2025 Meng, Han and Zhai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Rui Meng, mrmagic1985@126.com
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