REVIEW article
Front. Surg.
Sec. Orthopedic Surgery
Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1683843
This article is part of the Research TopicThe Homeostasis and Perturbations of the Skeletal System and Surrounding EnvironmentView all 6 articles
The Impact of Osteoporosis on Arthroscopic Rotator Cuff Repair and Postoperative Tendon-to-Bone Healing
Provisionally accepted
- 苏州市中医医院, 江苏省苏州市, China
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This review explores the impact of osteoporosis on arthroscopic rotator cuff repair and subsequent tendon healing, focusing on challenges such as anchor fixation failure, intraoperative fractures, and limited surgical visibility. It examines how osteoporosis disrupts the tendon healing microenvironment post-surgery through mechanisms involving bone metabolism, growth factors, the immune system, sex hormones, oxidative stress, and adipose infiltration. Effective surgical planning is crucial to mitigate osteoporosis's adverse effects on rotator cuff repair. The paper offers recommendations for optimizing surgical strategies, including anchor selection, placement, and fixation techniques. Additionally, it highlights the potential of anti-osteoporotic drugs and biological therapies to improve tendon-bone union and enhance clinical outcomes. For cases of inevitable repair failure, remedial strategies are proposed to inform clinical practice.
Keywords: Osteoporosis, Rotator cuff injury, Shoulder arthroscopy, tendon-to-bone healing, re-tear
Received: 11 Aug 2025; Accepted: 07 Oct 2025.
Copyright: © 2025 He, Chen, Wu, Zhang, You, Lai, Jiang and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: GuanHong Liu, liuguan58@126.com
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