Frontiers in Systems Biology

Volume 5 - 2025

Review

Published on 08 Aug 2025

Unraveling the role of mobile genetic elements in antibiotic resistance transmission and defense strategies in bacteria

Ranjith Kumavath
Puja Gupta
Eswar Rao Tatta
Mahima S. Mohan
Simi Asma Salim
Siddhardha Busi

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1557413

3,706 views
4 citations

Original Research

Published on 30 Jul 2025

A Pseudomonas fluorescens AND-gate biosensor for protein expression at plant root proximity

Nico van Donk
Antoine Raynal
Enrique Asin-Garcia

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1620608

2,161 views

Methods

Published on 03 Jul 2025

Learning Gaussian graphical models from correlated data

Zeyuan Song
Sophia Gunn
Stefano Monti
Gina M. Peloso
Ching-Ti Liu
Kathryn Lunetta
Paola Sebastiani

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1589079

1,446 views

Original Research

Published on 01 Jul 2025

Inflammation mediated brain damage and cytokine expression in a maternally derived murine model for preterm hypoxic-ischemic encephalopathy

Tyler C. Hillman
Braeden Jacobson
Kiara Piaggio Hurtado De Medoza
Marlene Lopez
Nicholas Iwakoshi
Christopher G. Wilson

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1517712

2,415 views

Perspective

Published on 30 May 2025

Exploring the disconnect: mechanisms underpinning the absence of physical function improvement with SGLT2 inhibitors

Cian Sutcliffe
Jack A. Sargeant
Thomas Yates
Melanie J. Davies
Luke A. Baker

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1593229

1,852 views

Mini Review

Published on 30 May 2025

Enzyme-displaying spores as a novel strategy for mixed fiber textile recycling

Matti Lehmann
Max Herrmann

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1603731

2,372 views

Original Research

Published on 21 May 2025

Mathematical modeling of pharmacokinetics and pharmacodynamics of losartan in relation to CYP2C9 allele variants

Dmitry Babaev
Elena Kutumova
Fedor Kolpakov

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1504077

2,350 views
2 citations

Opinion

Published on 29 Apr 2025

Biotechnology systems engineering: preparing the next generation of bioengineers

Sebastián Espinel-Ríos

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1583534

14,141 views

Review

Published on 16 Apr 2025

The role of probiotics, prebiotics, and synbiotics in the treatment of inflammatory bowel diseases: an overview of recent clinical trials

Fayez Yassine
Adam Najm
Melhem Bilen

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1561047

8,595 views
5 citations

Specialty Grand Challenge

Published on 13 Mar 2025

Scientia machina: a proposed conceptual framework for a technology-accelerated system of biomedical science

Sean T. Manion

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1576989

2,425 views

Volume 4 - 2024

Review

Published on 07 Jan 2025

A multi-omics strategy to understand PASC through the RECOVER cohorts: a paradigm for a systems biology approach to the study of chronic conditions

Jun Sun
Masanori Aikawa
Hassan Ashktorab
Noam D. Beckmann
Michael L. Enger
Joaquin M. Espinosa
Xiaowu Gai
Benjamin D. Horne
Paul Keim
Jessica Lasky-Su

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1422384

6,235 views
3 citations

Original Research

Published on 03 Jan 2025

Improvement in the prediction power of an astrocyte genome-scale metabolic model using multi-omic data

Andrea Angarita-Rodríguez
Nicolás Mendoza-Mejía
Janneth González
Jason Papin
Andrés Felipe Aristizábal
Andrés Pinzón

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1500710

2,742 views

Original Research

Published on 12 Dec 2024

Immune disease dialogue of chemokine-based cell communications as revealed by single-cell RNA sequencing meta-analysis

Mouly F. Rahman
Andre H. Kurlovs
Munender Vodnala
Elamaran Meibalan
Terry K. Means
Nima Nouri
Emanuele de Rinaldis
Virginia Savova

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1466368

4,592 views
2 citations

Methods

Published on 18 Nov 2024

An exploration of testing genetic associations using goodness-of-fit statistics based on deep ReLU neural networks

Xiaoxi Shen
Xiaoming Wang

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1460369

1,484 views
1 citation

Mini Review

Published on 13 Nov 2024

Interplay of circular RNAs in gastric cancer - a systematic review

Dipanjan Guha
Jit Mondal
Anirban Nandy
Sima Biswas
Angshuman Bagchi

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1497510

1,476 views
2 citations

Specialty Grand Challenge

Published on 06 Nov 2024

Bridging complexity through integrative systems neuroscience

Eric H. Chang

Frontiers in Systems Biology

doi 10.3389/fsysb.2024.1487298

4,105 views