Unraveling GI Cancer Heterogeneity Through Single-Cell Multi-Omics Approaches

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Articles

ORIGINAL RESEARCH

Accepted on 29 Aug 2025

Single-cell RNA Profiling of Colorectal Granular-type Laterally Spreading Tumor Uncovers Progression Trajectory Toward Carcinoma and Transcriptional Signatures Favoring Lateral Morphogenesis

Yueqing Gong
Yuxin Zhang
Xun Liu
Rongli Cui
Jingjing Lu
Jun LI
Fang Gu
Jing Zhang
Weiwei Fu
Shigang Ding

doi 10.3389/fonc.2025.1552841

ORIGINAL RESEARCH

Published on 03 Jun 2025

Deep spatial sequencing revealing differential immune responses in human hepatocellular carcinoma

Yan-Ping Yu
Caroline Obert
Bao-Guo Ren
Marielle Krivit
Kyle Metcalfe
Jia-Jun Liu
Tuval Ben-Yehezkel
Silvia Liu
Jian-Hua Luo

doi 10.3389/fcell.2025.1600129

1,191 views

ORIGINAL RESEARCH

Published on 13 Feb 2025

Distinct gene signatures define the epithelial cell features of mucinous appendiceal neoplasms and pseudomyxoma metastases

Carlos Ayala
Anuja Sathe
Xiangqi Bai
Susan M. Grimes
Jeanne Shen
George A. Poultsides
Byrne Lee
Hanlee P. Ji

doi 10.3389/fgene.2025.1536982

1,631 views

ORIGINAL RESEARCH

Published on 23 Oct 2024

Single-cell transcriptome analysis identifies a novel tumor-associated macrophage subtype predicting better prognosis in pancreatic ductal adenocarcinoma

Xiaonan Wang
Dongyi Li
Bo Zhu
Zichun Hua

doi 10.3389/fcell.2024.1466767

3,640 views
4 citations

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Frontiers in Genetics

Frontiers in Genetics

Statistical Genetics and Methodology
Cancer Genetics and Oncogenomics

Participating Journals

Frontiers in Cell and Developmental Biology
- Cancer Cell Biology
- 4.3 impact factor
- 11.4 citescore

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