Unraveling GI Cancer Heterogeneity Through Single-Cell Multi-Omics Approaches

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ORIGINAL RESEARCH

Published on 12 Sep 2025

Single-cell RNA profiling of colorectal granular-type laterally spreading tumor uncovers progression trajectory toward carcinoma and transcriptional signatures favoring lateral morphogenesis

Yueqing Gong
Yuxin Zhang
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Rongli Cui
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Jun Li
Fang Gu
Jing Zhang
Shigang Ding
Weiwei Fu

doi 10.3389/fonc.2025.1552841

976 views

ORIGINAL RESEARCH

Published on 03 Jun 2025

Deep spatial sequencing revealing differential immune responses in human hepatocellular carcinoma

Yan-Ping Yu
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Silvia Liu
Jian-Hua Luo

doi 10.3389/fcell.2025.1600129

1,549 views

ORIGINAL RESEARCH

Published on 13 Feb 2025

Distinct gene signatures define the epithelial cell features of mucinous appendiceal neoplasms and pseudomyxoma metastases

Carlos Ayala
Anuja Sathe
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Susan M. Grimes
Jeanne Shen
George A. Poultsides
Byrne Lee
Hanlee P. Ji

doi 10.3389/fgene.2025.1536982

1,956 views

ORIGINAL RESEARCH

Published on 23 Oct 2024

Single-cell transcriptome analysis identifies a novel tumor-associated macrophage subtype predicting better prognosis in pancreatic ductal adenocarcinoma

Xiaonan Wang
Dongyi Li
Bo Zhu
Zichun Hua

doi 10.3389/fcell.2024.1466767

4,356 views
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Frontiers in Genetics

Frontiers in Genetics

Statistical Genetics and Methodology
Cancer Genetics and Oncogenomics

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Frontiers in Cell and Developmental Biology
- Cancer Cell Biology
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