New Tumor Immune Checkpoints and Their Applications in Tumor Immunotherapy

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ORIGINAL RESEARCH

Published on 09 Dec 2025

Temporal changes in tongue color during immune checkpoint inhibitor therapy in patients with non-small-cell lung cancer: a prospective observational study using digital tongue diagnosis

Eunbyul Cho
Woosu Choi
Jun Hyeok Lim
Ji Woong Son
Seung Hun Jang
Seung Hyeun Lee
Jong Gwon Choi
In-Jae Oh
Tae-Won Jang
5 more
Mi-Kyung Jeong

doi 10.3389/or.2025.1697252

343 views

ORIGINAL RESEARCH

Published on 25 Nov 2025

Redox phenotype confers T cell-exclusion microenvironment and resistance to immunotherapy by suppressing STING/MDA5 expression and interferon signaling in lung cancers harboring KEAP1/STK11 mutations

Ashish Shrestha
Yangchan Li
Lixia Huang
Shaoli Li
Yanbin Zhou
Jincui Gu
Ziying Lin

doi 10.3389/fonc.2025.1676797

579 views

CASE REPORT

Published on 24 Nov 2025

Complete remission of advanced MSI-H rectal cancer in a young patient treated with nivolumab: a case report and critical appraisal of the literature

Marian Liberko
Renata Soumarova

doi 10.3389/fonc.2025.1680308

718 views

BRIEF RESEARCH REPORT

Published on 02 Oct 2025

Evaluating the impact of immune checkpoint inhibitors on liver steatosis and function: a retrospective cohort analysis

Sophie K. Schellhammer
Jessica Quintos Day
Run Fan
Fei Ye
Virginia Planz
Douglas B. Johnson

doi 10.3389/fonc.2025.1683982

1,242 views

CASE REPORT

Published on 25 Sep 2025

Case Report: Bowen’s disease treated with PD-1 inhibitor and chemotherapy

Xiaohui Xie
Qinyang Chen
Jian Zhang
Xiaodong Peng

doi 10.3389/fonc.2025.1654431

2,611 views

REVIEW

Published on 04 Sep 2025

Mechanisms, advances, and challenges of immunotherapy in gastric cancer

Zixin Wang
Tengjiao Wang

doi 10.3389/fimmu.2025.1639487

1,959 views
1 citation

TECHNOLOGY AND CODE

Published on 01 Aug 2025

Enhancing head and neck cancer detection accuracy in digitized whole-slide histology with the HNSC-classifier: a deep learning approach

Haiyang Yu
Wang Yu
Yuan Enwu
Jun Ma
Xin Zhao
Linlin Zhang
Fang Yang

doi 10.3389/fmolb.2025.1652144

1,723 views

REVIEW

Published on 31 Jul 2025

The dual role of Piezo1 in tumor cells and immune cells: a new target for cancer therapy

Peng Qu
Hongyan Zhang

doi 10.3389/fimmu.2025.1635388

4,841 views
3 citations

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Frontiers in Molecular Biosciences

Molecular Diagnostics and Therapeutics

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