Colorectal cancer (CRC) ranks as the third most prevalent cancer globally and stands as the second leading cause of cancer-related mortality. Despite progress in screening and various treatments, the development of resistance to drugs poses a significant hurdle, particularly for those with advanced stages of the disease. These challenges underscore the critical demand for new therapeutic approaches to improve survival and patient outcomes in CRC.
This Research Topic aims to explore the latest advancements and innovative strategies in the clinical integration of targeted therapies, prognostic assessments, and effective management of pain associated with colorectal cancer. Emphasizing a multidisciplinary collaboration among surgeons, anesthesiologists, and researchers, this initiative seeks to enhance the clinical outcomes for patients with advanced disease, setting new benchmarks in diagnostic and therapeutic protocols.
To gather further insights into these areas, we welcome contributions from international researchers and clinicians, including clinical trials, basic science studies, and comprehensive reviews, but not limited to the following themes:
-Development and integration of minimally invasive surgical techniques or novel therapies in clinical settings.
-Examination of patient quality of life post-surgery or chemotherapy, alongside effective pain management strategies.
-Evaluating integrative therapies designed to boost survival rates and prevent tumor metastasis.
-Innovations in immune checkpoint inhibitors, monoclonal antibodies, and other targeted drugs for CRC.
-Assessments of the efficacy and side effects of combined treatment modalities including chemotherapy and surgery.
Keywords: Colorectal cancer, novel therapies, pain management, drug resistance, tumor metastasis
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
