Decoding the Gut-Brain Axis: Implications for Neurodegenerative Disease Therapies

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STUDY PROTOCOL

Published on 23 Sep 2025

Study protocol for design of a personalized dietary supplement based on the gut microbiota of Alzheimer’s patients and evaluation of its effects in a pilot randomized controlled trial

Sara Clemente-Velasco
Beatriz de Lucas
Mariangela Tabone
Carlo Bressa
María del Rocío González-Soltero
Sara Martínez-López
María Bailén
Diego Domínguez-Balmaseda
Nazareth Castellanos
6 more
Mar Larrosa

doi 10.3389/fnut.2025.1653841

518 views

REVIEW

Accepted on 11 Sep 2025

The Microbiota–Gut–Brain Axis in Mental and Neurodegenerative Disorders: Opportunities for Prevention and Intervention

Lidya K. Yassin
Jurga Skrabulyte-Barbulescu
Shamsa H. Alshamsi
Sara Saeed
Shamma H. Alkuwaiti
Saif Almazrouei
Abeer Alnuaimi
Shamsa BaniYas
Dana Aldhaheri
2 more
Mohammad I. K. Hamad

doi 10.3389/fnagi.2025.1667448

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Frontiers in Aging Neuroscience

Frontiers in Aging Neuroscience

Neuroinflammation and Neuropathy

Participating Journals

Frontiers in Neuroscience
- Gut-Brain Axis
- 3.2 impact factor
- 6.6 citescore

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