Patent Foramen Ovale: Advances in Mechanisms, Diagnosis, and Therapy

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ORIGINAL RESEARCH

Accepted on 02 Dec 2025

Diaphragmatic Downward Excursion as a Novel Metric for assessing Valsalva Maneuver efficacy in Patent Foramen Ovale Detection by Contrast Transthoracic Echocardiography

Yun Li
Anni Chen
Jianbo Zhu
Lei Zhu
Turgunov Boburjon
Zhenzhen Jiang
Xiatian Liu

CASE REPORT

Published on 29 Aug 2025

Case Report: Is there an age cutoff beyond which PFO closure should not be offered?

Eustaquio Maria Onorato
Eleonora Melotti
Marco Doldi
Giovanni Monizzi
Angelo Mastrangelo
Vincenzo Mallia
Francesca Giacomazzi
Daniele Andreini
Antonio Luca Bartorelli

doi 10.3389/fcvm.2025.1622543

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Frontiers in Cardiovascular Medicine

Frontiers in Cardiovascular Medicine

Structural Interventional Cardiology

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