Chemical Signals | List of Frontiers open access articles

Original Research

Published on 10 Nov 2025

Elucidation of anti-SARS-CoV-2 and anti-inflammatory bioactives in Qingyan Dropping Pills via integrated in silico screening and bioactivity validation

in Infectious Diseases: Pathogenesis and Therapy

Liting Liu
Xinru Li
Xinyue Wang
Peng Zhang
Qi Yang
Tong Geng
Yuefei Wang
Junhua Zhang
Changjian Wang
Jing Yang

Frontiers in Medicine

doi 10.3389/fmed.2025.1684713

496 views

Study Protocol

Published on 10 Nov 2025

The effects of rTMS combined with blood flow restriction low-intensity resistance training on skeletal muscle mass, strength, and physical function in postmenopausal women: a single-blind randomized controlled trial protocol

in Aging in Women

Xiangdi Dai
Yuxiang Wu
Yuan Yuan
Binhua Lu
Xiaowei Wang
Guodong Xu
Jie Zhuang

Frontiers in Global Women's Health

doi 10.3389/fgwh.2025.1681138

326 views

Review

Published on 10 Nov 2025

The antitumor potential of Polygonatum spp.: a narrative review of traditional uses, bioactive metabolites, and multi-targeted mechanisms

in Ethnopharmacology

Mengqin Zhu
Guang Chen
Jinyu Li
Chang Yi
Yanfeng Yuan
Wenlong Liu
Xili Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1662839

319 views

Original Research

Published on 10 Nov 2025

Caffeine restricts hepatitis B virus transcription by inhibiting γ-H2AX formation

in Virology

Fangli Liao
Siyi Sun
Wenjuan Huang
Liping Yang
Qin Hu
Weixian Chen
Chaolin Tu
Linshan Jiang

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1706957

407 views

Original Research

Published on 10 Nov 2025

Towards human cardiac new approach methodologies (NAMs) to evaluate the combination of repolarization prolonging and shortening drugs: a pilot study

in Cardiovascular and Hematologic Drugs

Robert M. Geiger
Carlos Serna
Bhavya Bhardwaj
Tromondae K. Feaster
Ksenia Blinova

Frontiers in Drug Discovery

doi 10.3389/fddsv.2025.1679626

243 views

Original Research

Published on 10 Nov 2025

The development of a mindful eating app for adolescents through mixed-methods feedback from adolescents with overweight or obesity

in Obesity and Nutrition in Adolescents

Monica Serrano-Gonzalez
Miranda Triedman
Amiya Mandapati
Joshua Ray Tanzer
Rochelle Rosen
Elissa Jelalian
Barbara Jandasek

Frontiers in Adolescent Medicine

doi 10.3389/fradm.2025.1667649

177 views

Mini Review

Published on 10 Nov 2025

A mini-review of mathematical methods in sprint performance

in Elite Sports and Performance Enhancement

Yuzhou Fan

Frontiers in Sports and Active Living

doi 10.3389/fspor.2025.1696505

139 views

Original Research

Published on 10 Nov 2025

Assessment of immune responses to Brucella abortus S19 vaccination in cattle and buffaloes

in Vaccines and Molecular Therapeutics

Rajeswari Shome
Prabhakar Yallanur Konda
Somy Skariah
Gandu Shanmugam
Praveen Kumar Attiganahalli Muninarayanaswamy
Pavan Kalyan Nagaraja
Kirti Megha
Nanditha Thimmappa Rajeshwari
Nagalingam Mohandoss

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663259

429 views

Review

Published on 10 Nov 2025

Viral codon usage and the virus-host interactions

in Virology

Thanyaporn Sirihongthong
Prasert Auewarakul

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1711603

468 views

Original Research

Published on 10 Nov 2025

Forecasting bond strength of various FRP bars with different surface characteristics in concrete using machine learning models

in Computational Methods in Structural Engineering

Ameer M. Salih
Aso A. Abdalla
Sardar R. Mohammad Ali
Tre A. Abdullah

Frontiers in Built Environment

doi 10.3389/fbuil.2025.1692879

156 views

Study Protocol

Published on 10 Nov 2025

Clinical efficacy of soft tissue micro-adjustment combined with traction in pediatric atlantoaxial subluxation: a randomised controlled study protocol using musculoskeletal ultrasound technology

in Pediatric Orthopedics

Shuaizi Yin
Huasong Luo
Yinfeng Guo
Ge Cai
Ting Wu
Shuaiyu Ying
Xiao Zhang
Yi Sun
Xiayang Zeng

Frontiers in Pediatrics

doi 10.3389/fped.2025.1696802

343 views

Editorial

Published on 10 Nov 2025

Editorial: Intelligence and big data for sustainable urban built environment

in Urban Science

Chen Ren
Ruijun Zhang
Chaoqun Zhuang
Xiaojun Luo
Junqi Wang

Frontiers in Built Environment

doi 10.3389/fbuil.2025.1726686

237 views

Original Research

Published on 10 Nov 2025

Nutrient uptake under combined drought and salinity stress in hexaploid wheat species

in Plant Nutrition

Mohd. Kamran Khan

Frontiers in Plant Science

doi 10.3389/fpls.2025.1682258

277 views

Original Research

Published on 10 Nov 2025

Reshaping CAR-T cells through overexpression of T cell factor 1

in Cancer Immunity and Immunotherapy

Hao Yao
Yuntian Ding
Qian Chen
Huixiu Han
David Sedloev
Carsten Müller-Tidow
Tim Sauer
Anita Schmitt
Michael Schmitt
Lei Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623869

332 views

Original Research

Published on 10 Nov 2025

Enhancing the destruction of Burkholderia cepacia biofilm on stainless steel coupons by combining matrix-degrading enzymes with antimicrobials

in Biofilms

Yukta P. Gharat
Ahmed G. Abdelhamid
Ahmed E. Yousef

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1662291

475 views

Review

Published on 10 Nov 2025

Gut microbiota-derived metabolites modulate Treg/Th17 balance: novel therapeutic targets in autoimmune diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Guolin Li
Yu Xiong
Zhimin Li
Qin Yu
Shiran Li
Jingxian Xie
Siyu Zeng
Dongke Yu
Yong Yang
Jiangping Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1710733

Articles

Elucidation of anti-SARS-CoV-2 and anti-inflammatory bioactives in Qingyan Dropping Pills via integrated in silico screening and bioactivity validation

The effects of rTMS combined with blood flow restriction low-intensity resistance training on skeletal muscle mass, strength, and physical function in postmenopausal women: a single-blind randomized controlled trial protocol

The antitumor potential of Polygonatum spp.: a narrative review of traditional uses, bioactive metabolites, and multi-targeted mechanisms

Caffeine restricts hepatitis B virus transcription by inhibiting γ-H2AX formation

Towards human cardiac new approach methodologies (NAMs) to evaluate the combination of repolarization prolonging and shortening drugs: a pilot study

The development of a mindful eating app for adolescents through mixed-methods feedback from adolescents with overweight or obesity

A mini-review of mathematical methods in sprint performance

Assessment of immune responses to Brucella abortus S19 vaccination in cattle and buffaloes

Viral codon usage and the virus-host interactions

Forecasting bond strength of various FRP bars with different surface characteristics in concrete using machine learning models

Clinical efficacy of soft tissue micro-adjustment combined with traction in pediatric atlantoaxial subluxation: a randomised controlled study protocol using musculoskeletal ultrasound technology

Editorial: Intelligence and big data for sustainable urban built environment

Nutrient uptake under combined drought and salinity stress in hexaploid wheat species

Reshaping CAR-T cells through overexpression of T cell factor 1

Enhancing the destruction of Burkholderia cepacia biofilm on stainless steel coupons by combining matrix-degrading enzymes with antimicrobials

Gut microbiota-derived metabolites modulate Treg/Th17 balance: novel therapeutic targets in autoimmune diseases