Clinical Research Associate | List of Frontiers open access articles

Original Research

Published on 01 Oct 2025

Tuina therapy alleviates knee osteoarthritis by modulating PI3K/AKT/mTOR-mediated autophagy: an integrated machine learning and in vivo rat study

in Inflammation

Zhen Wang
Chi Zhao
Mengmeng Li
Lili Zhang
Jieyao Diao
Yiming Wu
Tao Yang
Mingwei Shi
Yang Lei
Yu Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1635818

523 views

Original Research

Published on 01 Oct 2025

Integrated proteomics and single-cell transcriptomics reveal potential therapeutic targets in Wilson’s disease patients

in Molecular Innate Immunity

Yue Qi
Minghui Sun
Fang Xu
Hao Zhou
Lihua Yuan
Xinlei Yu
Sirui Cao
Rui Hua

Frontiers in Immunology

doi 10.3389/fimmu.2025.1635137

395 views

Review

Published on 01 Oct 2025

Cell-free mitochondrial DNA as a pro-inflammatory agent in blood circulation: mechanisms, therapeutic implications, and clinical challenges in immune dysregulation

in Inflammation

Yangyang Zhao
Chunlei Wu
Xiaoxue Liang
Mengjiao Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640748

970 views

Original Research

Published on 01 Oct 2025

An investigation of the reach of the interim Canada dental benefit for children under 12 years of age

in Oral Epidemiology

Robert J. Schroth
Carol Youssef
Vivianne Cruz de Jesus
Olubukola O. Olatosi
Victor H. K. Lee
Saif Goubran
Eefa Khan
Anil Menon

Frontiers in Oral Health

doi 10.3389/froh.2025.1611815

315 views

Original Research

Published on 01 Oct 2025

Decoding honey-sweet flavored flue-cured tobacco from Guizhou with data science and flavoromics by volatile and cell wall components

in Analytical Chemistry

Risheng Zhong
Zhenchun Sun
Liang Feng
Haitao Chen
Shuqi Wang
Yechun Lin
Jie Sun
Ning Zhang
Huiying Zhang
Feng Wang

Frontiers in Chemistry

doi 10.3389/fchem.2025.1613828

1,006 views

Original Research

Published on 01 Oct 2025

Examining the benefit of L2 language proficiency on academic performance using Bayesian logistic modeling

in Performance Science

Taocheng Jiang
ZhiYi Zheng
Feng Wang

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1613695

2,123 views

Original Research

Published on 01 Oct 2025

Analysis of flavor characteristics of peanut porridge using gas chromatography-ion mobility spectrometry combined with intelligent sensory technology

in Food Chemistry

Bihua Yuan
Yun Tian
Xuan Zhu
Kaiqi Cheng
Wengang Jin
Qing Liu
Jing Li
Haiyan Sun

Frontiers in Nutrition

doi 10.3389/fnut.2025.1609333

461 views

Original Research

Published on 01 Oct 2025

The moderating role of social support in the relationship between alexithymia and problematic smartphone use among Chinese depressed adolescents: a cross-sectional study

in Adolescent and Young Adult Psychiatry

Shumiao Liu
Yufeng Wu
Fengxia Sun
Yongjie Zhou
Aihua Yin

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1650290

304 views

Original Research

Published on 01 Oct 2025

Multi-omics analysis of hepatic outcomes in T2DM-MAFLD patients treated with semaglutide: a single-centre, longitudinal, data-driven study

in Diabetes: Molecular Mechanisms

Shu Niu
Shuchun Chen
Di Wu
Chenxi Wang
Jianchao Xu
Jiantong Yin
Yubin Zhao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1650729

548 views

Original Research

Published on 01 Oct 2025

Combined biochar and DMPP reduce N2O emissions in wheat crops via microbial community modulation

in Plant Nutrition

Haizhong Wu
Dengxiao Zhang
Xiaobo Shen
Guozhen Ma
Qingsong Yuan
Hongjing Zhao
Shiliang Liu
Xiaolei Jie
Daichang Wang

Frontiers in Plant Science

doi 10.3389/fpls.2025.1647453

756 views

Original Research

Published on 01 Oct 2025

Effect of timing of surgery on postoperative complications and prognosis in elderly patients with hip fractures

in Geriatric Medicine

Zuobin Zhuo
Weijun Hong
Guangxi Ma

Frontiers in Medicine

doi 10.3389/fmed.2025.1646938

613 views

Original Research

Published on 01 Oct 2025

Migrant older adults’ perception of social support on subjective well-being: a mediating role of psychological resilience

in Aging and Public Health

Yuxi Liu
Qian Liu
Qihui Gan
Li Jia
Xianglei Zhu
Ruiming Liu
Jie Huang
Chonghua Wan
Qikang Chen

Frontiers in Public Health

doi 10.3389/fpubh.2025.1647544

318 views

Brief Research Report

Published on 01 Oct 2025

Paediatric CSF acylcarnitine reference ranges

in Metabolomics

Ontefetse Neo Plaatjie
A. Marceline Tutu Van Furth
Regan Solomons
Martijn Van Der Kuip
Shayne Mason

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1643667

913 views

Systematic Review

Published on 01 Oct 2025

Association of overt hypothyroidism with risks of cognitive impairment: a meta-analysis and systematic review

in Thyroid Endocrinology

Jinxin Zhu
Jialu Xu
Zhaoqing Li
Jia Liu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1643589

892 views

Original Research

Published on 01 Oct 2025

Vaccinating and non-vaccinating parents' attitudes toward influenza vaccination in children under 5 years old in Spain

in Infectious Diseases: Epidemiology and Prevention

Matilde Zornoza-Moreno
Susana Sánchez-Manresa
María Cruz Gómez-Moreno
María Pilar Ros Abellán
Jaime J. Pérez-Martín

Frontiers in Public Health

doi 10.3389/fpubh.2025.1644600

426 views

Review

Published on 01 Oct 2025

Bioactive compounds in Chinese herbal medicine: anti-inflammatory mechanisms targeting neurological disorders

in Nutrition, Psychology and Brain Health

Liangxue Zhang
Jiaxin Yang
Yuhua Yang
Min Yang
Juan Yang
Changyin Yu
Haiqing Zhang
Jinmei Tuo
Zucai Xu

Frontiers in Nutrition

doi 10.3389/fnut.2025.1646438

603 views

Articles

Tuina therapy alleviates knee osteoarthritis by modulating PI3K/AKT/mTOR-mediated autophagy: an integrated machine learning and in vivo rat study

Integrated proteomics and single-cell transcriptomics reveal potential therapeutic targets in Wilson’s disease patients

Cell-free mitochondrial DNA as a pro-inflammatory agent in blood circulation: mechanisms, therapeutic implications, and clinical challenges in immune dysregulation

An investigation of the reach of the interim Canada dental benefit for children under 12 years of age

Decoding honey-sweet flavored flue-cured tobacco from Guizhou with data science and flavoromics by volatile and cell wall components

Examining the benefit of L2 language proficiency on academic performance using Bayesian logistic modeling

Analysis of flavor characteristics of peanut porridge using gas chromatography-ion mobility spectrometry combined with intelligent sensory technology

The moderating role of social support in the relationship between alexithymia and problematic smartphone use among Chinese depressed adolescents: a cross-sectional study

Multi-omics analysis of hepatic outcomes in T2DM-MAFLD patients treated with semaglutide: a single-centre, longitudinal, data-driven study

Combined biochar and DMPP reduce N2O emissions in wheat crops via microbial community modulation

Effect of timing of surgery on postoperative complications and prognosis in elderly patients with hip fractures

Migrant older adults’ perception of social support on subjective well-being: a mediating role of psychological resilience

Paediatric CSF acylcarnitine reference ranges

Association of overt hypothyroidism with risks of cognitive impairment: a meta-analysis and systematic review

Vaccinating and non-vaccinating parents' attitudes toward influenza vaccination in children under 5 years old in Spain

Bioactive compounds in Chinese herbal medicine: anti-inflammatory mechanisms targeting neurological disorders