Developmental Pathways | List of Frontiers open access articles

Systematic Review

Published on 22 May 2025

Immunogenicity risk assessment for tailored mitigation and monitoring of biotherapeutics during development: recommendations from the European Immunogenicity Platform

in Vaccines and Molecular Therapeutics

Joanna Grudzinska-Goebel
Karin Benstein
Karien Bloem
Kyra J. Cowan
Boris Gorovits
Maria Jadhav
Melody Janssen
Vibha Jawa
Andrea Kiessling
Daniel Kramer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1581153

323 views

Original Research

Published on 22 May 2025

Clinical outcomes of newly diagnosed PCNSL treated with rituximab-methotrexate-cytarabine with or without ibrutinib: a retrospective study

in Cancer Immunity and Immunotherapy

Wenhua Wang
Bingyi Wang
Yifei Sun
Lihua Qiu
Zhengzi Qian
Shiyong Zhou
Zheng Song
Wei Li
Lanfang Li
Xianhuo Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1579483

Original Research

Published on 22 May 2025

Bupropion decreases plasma levels of asymmetric dimethylarginine and ameliorates renal injury by modulation of Ddah1, Oatp4c1, Oct2, and Mate1 in rats with adenine-induced chronic renal injury

in Renal Pharmacology

Lulu Huang
Yun Xiao
Xiaoyu Han
Yang Yu
Chao Zheng
Xiangdong Fang
Qing Li
Fanglan Liu
Chunhua Xia
Yongjie Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565713

Original Research

Published on 22 May 2025

Innate immune pathway activated mesenchymal stromal cells improve function and histologic outcomes in a rodent osteoarthritis model

in Tissue Engineering and Regenerative Medicine

Cody Plaisance
Lyndah Chow
Renata Impastato
Zoë J. Williams
Isabella Sabino
Katie J. Sikes
Kelly S. Santangelo
Steven Dow
Lynn M. Pezzanite

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1525969

192 views

Systematic Review

Published on 22 May 2025

Effects of exercise intervention on body morphology in obese college students: a systematic review and meta-analysis

in Public Health and Nutrition

Wengao Liao
Wenlu Yu
Yuanji Zhao
Zonglin Ma
Jie Xie

Frontiers in Public Health

doi 10.3389/fpubh.2025.1595862

112 views

Original Research

Published on 22 May 2025

Characterisation of the α-GOS profile of field pea and cowpea cultivars and their modulation through sustainable processing methods

in Sustainable Food Processing

Kalpana Tewari
Vaibhav Kumar
Ashok Kumar Parihar
Sudhir Kumar Jha
Kuldeep Kumar
Rishikesh Kumar
Man Mohan Deo
Surendra Kumar Meena
Rajeev Kumar
M. Senthil Kumar

Frontiers in Sustainable Food Systems

doi 10.3389/fsufs.2025.1600726

119 views

Original Research

Published on 22 May 2025

Unlocking the potential of wearable technology: Fitbit-derived measures for predicting ADHD in adolescents

in Autism and Other Neurodevelopmental Disorders

Muhammad Mahbubur Rahman

Frontiers in Child and Adolescent Psychiatry

doi 10.3389/frcha.2025.1504323

Original Research

Published on 22 May 2025

Multiomics analysis unveils key biomarkers during dynamic progress of IAV infection in mice

in Viral Immunology

Huan Lei
Yixi Xu
Hao Zhang
Bin Zhang
Wenjun Luo
Xiao Liu
Haijun Zhang
Jinming Yang
Wen Wen
Ping Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566690

117 views

Original Research

Published on 22 May 2025

Assessing smart cities' effectiveness: machine learning approaches

in Urban Economics

Oleh Berezsky
Olha Kovalchuk
Kateryna Berezka
Roman Ivanytskyy

Frontiers in Sustainable Cities

doi 10.3389/frsc.2025.1400917

257 views

Original Research

Published on 22 May 2025

Machine learning-driven prediction of cycloplegic refractive error in Chinese children

in Molecular and Cellular Pathology

Bichi Chen
Li Tian
Fuyue Tian
Qiaochu Yang
Ying Ruan
Ying Li
Min Cao
Chuanyan Wu
Maoyuan Yang
Suzhong Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608494

Original Research

Published on 22 May 2025

Development and temporal external validation of a novel nomogram for predicting one-year mortality in the older adult with hip fracture

in Geriatric Medicine

Yangfan Gong
Kai Zhang
Wei Chen
Qiqi Yang
Mingyue Shi
Zhao Dong
Zhuohao Yin
Yuyu Zhang
Wei Ge

Frontiers in Medicine

doi 10.3389/fmed.2025.1532196

170 views

Case Report

Published on 22 May 2025

A case report of small cell neuroendocrine carcinoma of the ovary and review of the literature

in Cancer Immunity and Immunotherapy

Ying Zhao
Fuli Kang
Xiangshu Kong
Ning Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1569011

Original Research

Published on 22 May 2025

Indoleamine 2,3-dioxygenase-1 expression in non-small-cell lung cancer: analyses of prevalence, clinical correlations and prognostic impact in 2 large patient cohorts

in Cancer Immunity and Immunotherapy

Francesco Agustoni
Hui Yu
Kim Ellison
Derek Smith
Paul Mitchell
Gareth Rivalland
Rafal Dziadziuszko
Dexiang Gao
Shengxiang Ren
Christopher J. Rivard

Frontiers in Immunology

doi 10.3389/fimmu.2025.1586782

Original Research

Published on 22 May 2025

Nutritional and sensory characteristics of developed wheat burger buns incorporated with different levels of steamed-squid (Loligo forbesii) powder

in Nutrition and Food Science Technology

Rehab F. M. Ali
Ayman M. El-Anany

Frontiers in Nutrition

doi 10.3389/fnut.2025.1615629

Review

Published on 22 May 2025

Deciphering the gut microbiome’s metabolic code: pathways to bone health and novel therapeutic avenues

in Bone Research

Daniel Hwang
Esther Chong
Yanxiu Li
Yanling Li
Kangsan Roh

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1553655

296 views

Original Research

Published on 22 May 2025

Triglyceride-glucose index as a predictor of one-year mortality in non-diabetic acute ischemic stroke

in Cardiovascular Endocrinology

Shengyuan Wang
Xianjia Ning
Jun Tu
Jinghua Wang
Yu Zhao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1523787

Articles

Immunogenicity risk assessment for tailored mitigation and monitoring of biotherapeutics during development: recommendations from the European Immunogenicity Platform

Clinical outcomes of newly diagnosed PCNSL treated with rituximab-methotrexate-cytarabine with or without ibrutinib: a retrospective study

Bupropion decreases plasma levels of asymmetric dimethylarginine and ameliorates renal injury by modulation of Ddah1, Oatp4c1, Oct2, and Mate1 in rats with adenine-induced chronic renal injury

Innate immune pathway activated mesenchymal stromal cells improve function and histologic outcomes in a rodent osteoarthritis model

Effects of exercise intervention on body morphology in obese college students: a systematic review and meta-analysis

Characterisation of the α-GOS profile of field pea and cowpea cultivars and their modulation through sustainable processing methods

Unlocking the potential of wearable technology: Fitbit-derived measures for predicting ADHD in adolescents

Multiomics analysis unveils key biomarkers during dynamic progress of IAV infection in mice

Assessing smart cities' effectiveness: machine learning approaches

Machine learning-driven prediction of cycloplegic refractive error in Chinese children

Development and temporal external validation of a novel nomogram for predicting one-year mortality in the older adult with hip fracture

A case report of small cell neuroendocrine carcinoma of the ovary and review of the literature

Indoleamine 2,3-dioxygenase-1 expression in non-small-cell lung cancer: analyses of prevalence, clinical correlations and prognostic impact in 2 large patient cohorts

Nutritional and sensory characteristics of developed wheat burger buns incorporated with different levels of steamed-squid (Loligo forbesii) powder

Deciphering the gut microbiome’s metabolic code: pathways to bone health and novel therapeutic avenues

Triglyceride-glucose index as a predictor of one-year mortality in non-diabetic acute ischemic stroke