Drug Design And Development | List of Frontiers open access articles

Original Research

Published on 08 Oct 2025

Risk factors and clinical outcomes of severe postoperative hypoxaemia following surgical repair of Stanford type A aortic dissection: a retrospective cohort study

in Intensive Care Medicine and Anesthesiology

Min Lin
Yuping Xiang
Tianhui Luo
Ling Zeng
Jingxiu Fan

Frontiers in Medicine

doi 10.3389/fmed.2025.1603262

262 views

Original Research

Published on 08 Oct 2025

Beyond mindfulness: the importance of body compassion in colorectal cancer distress

in Psycho-Oncology

Lauren A. Zimmaro
Aimee J. Christie
Andrew Nicklawsky
Jennifer K. Altman
James W. Carson
Christopher H. Lieu
Carolyn Y. Fang
Jennifer B. Reese

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1618389

2,587 views

Original Research

Published on 08 Oct 2025

Analysis of influential factors in laparoscopic myomectomy and estimation of hidden blood loss

in Obstetrics and Gynecological Surgery

Jingjing Lu
Lili Chu
Liliang Shen

Frontiers in Surgery

doi 10.3389/fsurg.2025.1614919

470 views

Original Research

Published on 08 Oct 2025

Unveiling the impact of interferon genes on the immune microenvironment of triple-negative breast cancer: identification of therapeutic targets

in RNA Bioinformatics

Ying Liu
Jiayi Cai
Aamir Fahira
Kai Zhuang
Jiaojiao Wang
Zhi Zhang
Lin Yan
Yong Liu
Defang Ouyang
Zunnan Huang

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1629526

735 views

Review

Published on 08 Oct 2025

Unraveling brucellosis: advances in pathogenesis, diagnostic strategies, therapeutic innovations, and public health perspectives

in Infectious Diseases: Pathogenesis and Therapy

Abdulaziz M. Almuzaini
Ayman Elbehiry

Frontiers in Medicine

doi 10.3389/fmed.2025.1629008

825 views

Case Report

Published on 08 Oct 2025

Case Report: Efficacy of preoperative conversion therapy with lenvatinib, toripalimab, and hepatic arterial infusion chemotherapy in an advanced hepatocellular carcinoma

in Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Jing Mao
Hengzhi Zhang
Xingxia Yang
Yanjun Yao
Xu Sun
Qiang Yan

Frontiers in Oncology

doi 10.3389/fonc.2025.1627281

671 views

Original Research

Published on 08 Oct 2025

Analysis of global, regional, and national burdens of neonatal encephalopathy from 1990 to 2021: insights from the Global Burden of Disease Study 2021

in Children and Health

Shujun Tan
Shala Mageziyi
Li Long
Naiyiman Dilimulati
Zhang Hui
Nuerya Rejiafu

Frontiers in Public Health

doi 10.3389/fpubh.2025.1627448

415 views

Original Research

Published on 08 Oct 2025

Auricular acupuncture as stress-relieving intervention for parents of infants in the neonatal intensive care unit: insights gained from a pilot study

in Maternal Health

Helle Haslund-Thomsen
Bettina Svelle
Christina Skoda
Malene Horskjær
Marie Germund Nielsen

Frontiers in Global Women's Health

doi 10.3389/fgwh.2025.1597105

442 views

Original Research

Published on 08 Oct 2025

Revised Peck’s formula for estimating pipeline’s settlement under the coupling effect of tunnelling and vehicle load

in Structural Sensing, Control and Asset Management

Shu Peng

Frontiers in Built Environment

doi 10.3389/fbuil.2025.1607111

750 views

Study Protocol

Published on 08 Oct 2025

Digital home-based multimodal prehabilitation of colorectal cancer patients prior to surgery (the dHOPE study): a non-inferiority clinical trial protocol

in Personalized Medicine

Guro Kleve
Chiara Dalla Santa
Felicia Kristiansen
Marita Tegnander
Victoria Buch
Cecilie Steen Hagemann
Marianne Helgheim
Parasto Engene
Henri Pesonen
Maiken Kojen Kleveland

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1609678

3,020 views

Case Report

Published on 08 Oct 2025

Case report: Abscopal response and reversal of PD-1 resistance in a patient with nephroblastoma following radiofrequency ablation

in Genitourinary Oncology

Mengyang Ju
Mingjuan Sun
Wenfeng Li
Sheng Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1640409

142 views

Policy and Practice Reviews

Published on 08 Oct 2025

“The birth of the association of European National Olympic Committees and its stakes during the 1960s to 1970s”

in Sports Politics, Policy and Law

Florent Lefèvre

Frontiers in Sports and Active Living

doi 10.3389/fspor.2025.1654715

462 views

Case Report

Published on 08 Oct 2025

Diagnosis and therapeutic strategies for primary bladder mucinous adenocarcinoma: a case report and literature review

in Genitourinary Oncology

Xi Cheng
Weibo Wang
Lexing Yang
Supeng Tai
Junyue Tao
Yao Fu
Jun Zhou

Frontiers in Oncology

doi 10.3389/fonc.2025.1652375

594 views

Original Research

Published on 08 Oct 2025

The adaptation triangle: a multivariate analysis of vulnerability, resilience and livelihood strategies in semi-arid regions of India

in Climate Adaptation

Bharath Kumar Mannepalli
Saket Kushwaha
Virendra Kamalvanshi
Pradip Kumar Parida
Evans Kemboi
Ankit Yadav
Prakhar Deep
Reshmi Mukherjee

Frontiers in Climate

doi 10.3389/fclim.2025.1674565

470 views

Original Research

Published on 08 Oct 2025

En bloc resection for primary spinal tumors with huge intrathoracic involvement: a surgical intervention for neurological decompression and oncological control

in Neuro-Oncology and Neurosurgical Oncology

Fangzhi Liu
Ben Wang
Jiacheng Liu
Xiaoguang Liu
Fengliang Wu
Hua Zhou
Lei Dang
Yan Li
Yanchao Tang
Xiao Liu

Frontiers in Neurology

doi 10.3389/fneur.2025.1661864

961 views

Perspective

Published on 08 Oct 2025

A human sentinel surveillance framework for comprehensive exposure assessment in occupational and environmental health

in Occupational Health and Safety

Emine Aktaş
Kaoutar Chbihi
Hilde De Raeve
Janne Goossens
Lode Godderis

Frontiers in Public Health

doi 10.3389/fpubh.2025.1641884

398 views

Articles

Risk factors and clinical outcomes of severe postoperative hypoxaemia following surgical repair of Stanford type A aortic dissection: a retrospective cohort study

Beyond mindfulness: the importance of body compassion in colorectal cancer distress

Analysis of influential factors in laparoscopic myomectomy and estimation of hidden blood loss

Unveiling the impact of interferon genes on the immune microenvironment of triple-negative breast cancer: identification of therapeutic targets

Unraveling brucellosis: advances in pathogenesis, diagnostic strategies, therapeutic innovations, and public health perspectives

Case Report: Efficacy of preoperative conversion therapy with lenvatinib, toripalimab, and hepatic arterial infusion chemotherapy in an advanced hepatocellular carcinoma

Analysis of global, regional, and national burdens of neonatal encephalopathy from 1990 to 2021: insights from the Global Burden of Disease Study 2021

Auricular acupuncture as stress-relieving intervention for parents of infants in the neonatal intensive care unit: insights gained from a pilot study

Revised Peck’s formula for estimating pipeline’s settlement under the coupling effect of tunnelling and vehicle load

Digital home-based multimodal prehabilitation of colorectal cancer patients prior to surgery (the dHOPE study): a non-inferiority clinical trial protocol

Case report: Abscopal response and reversal of PD-1 resistance in a patient with nephroblastoma following radiofrequency ablation

“The birth of the association of European National Olympic Committees and its stakes during the 1960s to 1970s”

Diagnosis and therapeutic strategies for primary bladder mucinous adenocarcinoma: a case report and literature review

The adaptation triangle: a multivariate analysis of vulnerability, resilience and livelihood strategies in semi-arid regions of India

En bloc resection for primary spinal tumors with huge intrathoracic involvement: a surgical intervention for neurological decompression and oncological control

A human sentinel surveillance framework for comprehensive exposure assessment in occupational and environmental health