Focused Review | List of Frontiers open access articles

Study Protocol

Published on 06 Aug 2025

Trial in progress: phase I study of non-viral gene-modified CAR-T cell therapy for malignant solid tumors expressing EPHB4 receptor (CARTiEr)

in Cancer Immunity and Immunotherapy

Chikako Funasaka
Yoichi Naito
Hitomi Kubota
Yukiko Ishiguro
Nozomu Fuse
Masashi Wakabayashi
Akihiro Sato
Junichiro Yuda
Genichiro Ishii
Toshihiro Suzuki

Frontiers in Oncology

doi 10.3389/fonc.2025.1633324

253 views

Original Research

Published on 06 Aug 2025

Machine learning–based quantification of overall and internal ultrasound characteristics for diagnosing malignant partially cystic thyroid nodules

in Thyroid Endocrinology

Yutong Zhang
Jue Jiang
Aqian Chen
Dong Zhang
Lirong Wang
Xin Yuan
Xin He
Shanshan Yu
Juan Wang
Qi Zhou

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1635122

162 views

Original Research

Published on 06 Aug 2025

Single-cell transcriptomic profiling reveals a novel signature of necrotizing granulomatous lesions in the lungs of Mycobacterium tuberculosis-infected C3HeB/FeJ mice

in Microbial Immunology

Shintaro Seto
Shiho Omori
Hajime Nakamura
Minako Hijikata
Naoto Keicho

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624072

271 views

Original Research

Published on 06 Aug 2025

The safety of percutaneous renal biopsy for acute kidney injury in metastatic renal cell cancer patients with reduced nephron mass

in Onconephrology

Tomaz Milanez
Vinay Srinivasan
Vladimir Premru
Miha Arnol
Janja Ocvirk
Edgar A. Jaimes

Frontiers in Nephrology

doi 10.3389/fneph.2025.1615779

286 views

Original Research

Published on 06 Aug 2025

A pharmacovigilance study of the association between linaclotide/plecanatide and muscle spasms based on food and drug administration adverse event reporting system

in Gastrointestinal and Hepatic Pharmacology

Xue Fan
Yuan Li
Xiangchun Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1635792

193 views

Review

Published on 06 Aug 2025

Mechanisms of traditional Chinese medicine regulating polycystic ovary syndrome through gut microbiota: a review

in Gut Endocrinology

Xiaomei Jiang
Yongfeng Wang
Yu Hua
Hong Tang
Heyue Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1610869

232 views

Systematic Review

Published on 06 Aug 2025

Incidence of pneumonitis with CTLA-4 inhibitors in non-small cell lung cancer: a systematic review and meta-analysis

in Pulmonary Medicine

Wei Li
Hao Xiong
Haiying Peng
Ting Yang
Li Fan
Yanlin Zhang

Frontiers in Medicine

doi 10.3389/fmed.2025.1614442

272 views

Mini Review

Published on 06 Aug 2025

Biomarkers to predict the severity of acute pancreatitis

in Gastroenterology

Xinwei Hao
Zimeng Wang
Xiaotong Niu
Longsong Li
Yawei Bi
Ningli Chai

Frontiers in Medicine

doi 10.3389/fmed.2025.1619087

124 views

Original Research

Published on 06 Aug 2025

Network pharmacology and molecular docking analysis on molecular targets and mechanisms of scar healing ointment in the treatment of hypertrophic scars

in Experimental Pharmacology and Drug Discovery

Lijuan Jiang
Xiandong Zeng
Hongjun Li
Jingping Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1511570

169 views

Original Research

Published on 06 Aug 2025

CHML regulates migration and invasion in hepatocellular carcinoma via transcriptional and metabolic reprogramming

in Cancer Metabolism

Huanqian Cao
Siyu Wang
Li Zhang
Heying Xie
Yiqiong Liu
Ruijiao Kong
Yin Jia
Ling Lu
Junfeng Jiang
Shanrong Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1575809

167 views

Brief Research Report

Published on 06 Aug 2025

Genomic trajectories of colorectal cancer with choroidal metastasis: longitudinal insights from tissue and liquid biopsy via next-generation sequencing

in Cancer Genetics and Oncogenomics

Alessandro Ottaiano
Luisa Circelli
Carmine Picone
Monica Ianniello
Raffaella Ruggiero
Roberto Sirica
Mariachiara Santorsola
Anna Chiara Carratù
Nadia Petrillo
Gaetana Cerbone

Frontiers in Genetics

doi 10.3389/fgene.2025.1632580

200 views

Original Research

Published on 06 Aug 2025

Global burden of anemia attributable to non-communicable diseases: GBD 2021 analysis and projections

in Nutritional Epidemiology

Danqing Yu
Yulu Ni
Kai Chen
Haiyan Xu
Xin Huang
Yinhui He

Frontiers in Nutrition

doi 10.3389/fnut.2025.1557986

189 views

Original Research

Published on 06 Aug 2025

Recipient warm ischemic time negatively influences biliary complications and graft survival – a single center retrospective analysis

in Hepatology

Sophie Reichelt
Alexander Semaan
Philipp Lutz
Jörg C. Kalff
Cornelius J. van Beekum
Steffen Manekeller

Frontiers in Gastroenterology

doi 10.3389/fgstr.2025.1601741

197 views

Original Research

Published on 06 Aug 2025

Lifestyle factors and hyperuricemia risk: a prospective cohort study of 14,635 participants examining the protective role of daily stair climbing

in Nutrition and Metabolism

Wenkui Yin
Donglin Luo
Wenying Huang
Haichao Jiang
Yahai Wang
Haixia Qi

Frontiers in Nutrition

doi 10.3389/fnut.2025.1635746

176 views

Original Research

Published on 06 Aug 2025

Association of inflammation geriatric nutritional risk index with all-cause and CVD mortality in patients with osteoarthritis

in Nutritional Epidemiology

Gaohua Cao
Yunxuan Zou
Lei Tan
Yuanyuan Zhou
Shaodong Xie
Ke Jie
He Chen

Frontiers in Nutrition

doi 10.3389/fnut.2025.1616413

286 views

Original Research

Published on 06 Aug 2025

Gender, residence, and socioeconomic differences in the relationship of nutrition literacy with vegetable and fruit intake in adults

in Nutritional Epidemiology

Xi Tian
Xiaoting Hu
Yuhui Sun
Huaqing Liu

Frontiers in Nutrition

doi 10.3389/fnut.2025.1606315

200 views

Articles

Trial in progress: phase I study of non-viral gene-modified CAR-T cell therapy for malignant solid tumors expressing EPHB4 receptor (CARTiEr)

Machine learning–based quantification of overall and internal ultrasound characteristics for diagnosing malignant partially cystic thyroid nodules

Single-cell transcriptomic profiling reveals a novel signature of necrotizing granulomatous lesions in the lungs of Mycobacterium tuberculosis-infected C3HeB/FeJ mice

The safety of percutaneous renal biopsy for acute kidney injury in metastatic renal cell cancer patients with reduced nephron mass

A pharmacovigilance study of the association between linaclotide/plecanatide and muscle spasms based on food and drug administration adverse event reporting system

Mechanisms of traditional Chinese medicine regulating polycystic ovary syndrome through gut microbiota: a review

Incidence of pneumonitis with CTLA-4 inhibitors in non-small cell lung cancer: a systematic review and meta-analysis

Biomarkers to predict the severity of acute pancreatitis

Network pharmacology and molecular docking analysis on molecular targets and mechanisms of scar healing ointment in the treatment of hypertrophic scars

CHML regulates migration and invasion in hepatocellular carcinoma via transcriptional and metabolic reprogramming

Genomic trajectories of colorectal cancer with choroidal metastasis: longitudinal insights from tissue and liquid biopsy via next-generation sequencing

Global burden of anemia attributable to non-communicable diseases: GBD 2021 analysis and projections

Recipient warm ischemic time negatively influences biliary complications and graft survival – a single center retrospective analysis

Lifestyle factors and hyperuricemia risk: a prospective cohort study of 14,635 participants examining the protective role of daily stair climbing

Association of inflammation geriatric nutritional risk index with all-cause and CVD mortality in patients with osteoarthritis

Gender, residence, and socioeconomic differences in the relationship of nutrition literacy with vegetable and fruit intake in adults